Abscisic acid negatively regulates the Polycomb-mediated H3K27me3 through the PHD-finger protein, VIL1.
Abscisic acid negatively regulates the Polycomb-mediated H3K27me3 through the PHD-finger protein, VIL1.
复制标题
脱落酸通过PhD-Finger蛋白VIL1负性调节Polycomb介导的H3K27me3。
DOI:
10.1111/nph.18156
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发表时间:
2022-08
期刊:
影响因子:
9.4
通讯作者:
Sung, Sibum
中科院分区:
文献类型:
--
作者:
Zong, Wei;Kim, Junghyun;Bordiya, Yogendra;Qiao, Hong;Sung, Sibum
Polycomb dictates developmental programs in higher eukaryotes, including flowering plants. A phytohormone, Abscisic acid (ABA), plays a pivotal role in seed and seedling development and mediates responses to multiple environmental stresses, such as salinity and drought. In this study, we show that ABA affects the Polycomb Repressive Complex 2 (PRC2)-mediated Histone H3 Lys 27 trimethylation (H3K27me3) through VIN3-LIKE1/VERNALIZATION 5 (VIL1/VRN5) to fine-tune the timely repression of ABSCISIC ACID INSENSITIVE 3 (ABI3) and ABSCISIC ACID INSENSITIVE 4 (ABI4) in Arabidopsis thaliana. vil1 mutants exhibit hypersensitivity to ABA during early seed germination and show enhanced drought tolerance. Our study revealed that the ABA signaling pathway utilizes a facultative component of the chromatin remodeling complex to demarcate the level of expression of ABA-responsive genes.
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