Retrospective Analysis of Aetiological Agents Associated with Pulmonary Mycosis Secondary to Enteric Salmonellosis in Six Horses by Panfungal Polymerase Chain Reaction.

Retrospective Analysis of Aetiological Agents Associated with Pulmonary Mycosis Secondary to Enteric Salmonellosis in Six Horses by Panfungal Polymerase Chain Reaction.
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DOI:
10.1016/j.jcpa.2019.10.002
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发表时间:
2020-01
影响因子:
0.8
通讯作者:
Rech RR
Rech RR
中科院分区:
农林科学4区
文献类型:
--
作者:
Hensel M;Meason-Smith C;Plumlee QD;Myers AN;Coleman MC;Lawhon S;Rodrigues Hoffmann A;Rech RR

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Pulmonary mycosis secondary to enterocolitis is an uncommon diagnosis in equine medicine but is thought to result from mucosal compromise and translocation of enteric fungi. The etiologic agent associated with translocation is often identified based on fungal culture or hyphal features in histologic sections. In order to better understand the etiologic agents involved, 6 horses diagnosed with Salmonella enteritis and concurrent pulmonary mycosis were retrospectively identified through a database search of a veterinary teaching hospital records. The cases were subjected to PCR and sequencing of the internal transcribed spacer 2 (ITS-2) located between 5.8S and 28S rRNA genes to identify the etiologic agent involved. Sequencing identified Aspergillus fumigatus, Aspergillus flavus, Fusarium sp., Cladosporium spp., and Curvularia sp. A single case had a dual infection with Fusarium sp. and Aspergillus fumigatus.
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