Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature).

Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature).
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DOI:
10.3390/ijms221910554
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发表时间:
2021-09-29
影响因子:
5.6
通讯作者:
Romanowicz H
Romanowicz H
中科院分区:
生物学2区
文献类型:
--
作者:
Smolarz B;Szyłło K;Romanowicz H

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子宫内膜异位症是一种“神秘”的疾病,其确切原因尚未确定。在病因中,列出了先天性、环境、表观遗传、自身免疫和过敏因素。据信,子宫内膜异位病灶形成的主要机制是月经逆行,即,经血通过输卵管进入腹膜腔,脱落的子宫内膜细胞着床。然而,由于这种机制也在健康女性中观察到,其他因素也必须参与子宫内膜异位症病灶的形成。子宫内膜异位症是许多妇女不孕、慢性疼痛和生活质量恶化的原因。这也给卫生系统带来了沉重的财政负担。本文提出了一个审查的文献对乳腺癌的疾病影响妇女在世界各地。
Endometriosis is a “mysterious” disease and its exact cause has not yet been established. Among the etiological factors, congenital, environmental, epigenetic, autoimmune and allergic factors are listed. It is believed that the primary mechanism of the formation of endometriosis foci is retrograde menstruation, i.e., the passage of menstrual blood through the fallopian tubes into the peritoneal cavity and implantation of exfoliated endometrial cells. However, since this mechanism is also observed in healthy women, other factors must also be involved in the formation of endometriosis foci. Endometriosis is in many women the cause of infertility, chronic pain and the deterioration of the quality of life. It also represents a significant financial burden on health systems. The article presents a review of the literature on endometriosis—a disease affecting women throughout the world.
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发表时间: 2013
期刊: PloS one
影响因子: 3.7
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