"Snake-oil," "quack medicine," and "industrially cultured organisms:" biovalue and the commercialization of human microbiome research.
"Snake-oil," "quack medicine," and "industrially cultured organisms:" biovalue and the commercialization of human microbiome research.
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DOI：
10.1186/1472-6939-13-28
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发表时间：
2012-10-30
影响因子：
2.7
通讯作者：
McGuire AL
中科院分区：
文献类型：
--
作者：
Slashinski MJ;McCurdy SA;Achenbaum LS;Whitney SN;McGuire AL
Continued advances in human microbiome research and technologies raise a number of ethical, legal, and social challenges. These challenges are associated not only with the conduct of the research, but also with broader implications, such as the production and distribution of commercial products promising maintenance or restoration of good physical health and disease prevention. In this article, we document several ethical, legal, and social challenges associated with the commercialization of human microbiome research, focusing particularly on how this research is mobilized within economic markets for new public health uses. We conducted in-depth, semi-structured interviews (2009–2010) with 63 scientists, researchers, and National Institutes of Health project leaders (“investigators”) involved with human microbiome research. Interviews explored a range of ethical, legal, and social dimensions of human microbiome research, including investigators’ perspectives on commercialization. Using thematic content analysis, we identified and analyzed emergent themes and patterns. Investigators discussed the commercialization of human microbiome research in terms of (1) commercialization, probiotics, and issues of safety, (2) public awareness of the benefits and risks of dietary supplements, and (3) regulation. The prevailing theme of ethical, legal, social concern focused on the need to find a balance between the marketplace, scientific research, and the public’s health. The themes we identified are intended to serve as points for discussions about the relationship between scientific research and the manufacture and distribution of over-the-counter dietary supplements in the United States.
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DOI：
10.1525/jer.2012.7.3.1
发表时间：
2012-07
期刊：
Journal of empirical research on human research ethics : JERHRE
影响因子：
--
作者：
McGuire AL;Achenbaum LS;Whitney SN;Slashinski MJ;Versalovic J;Keitel WA;McCurdy SA
通讯作者：
McCurdy SA
影响因子：
4.2
作者：
Bailey, Regan L.;Gahche, Jaime J.;Picciano, Mary Frances
通讯作者：
Picciano, Mary Frances
影响因子：
--
作者：
Hasler, Clare M.;Brown, Amy C.
通讯作者：
Brown, Amy C.
开发用于监测微生物群落结构变化的荧光团-核糖体 DNA 限制性分型方法
影响因子：
2.8
作者：
Wang, Tingting;Zhang, Xiaojun;Zhao, Liping
通讯作者：
Zhao, Liping
影响因子：
9.8
作者：
Sharp, Richard R.;Achkar, Jean-Paul;Brinich, Margaret A.;Farrell, Ruth M.
通讯作者：
Farrell, Ruth M.