Helping patients make informed choices about probiotics: a need for research.
Helping patients make informed choices about probiotics: a need for research.
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DOI：
10.1038/ajg.2008.68
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发表时间：
2009-04
影响因子：
9.8
通讯作者：
Farrell, Ruth M.
中科院分区：
文献类型：
--
作者：
Sharp, Richard R.;Achkar, Jean-Paul;Brinich, Margaret A.;Farrell, Ruth M.
尽管有证据表明益生菌会带来巨大的健康风险，特别是对免疫功能低下或病情严重的患者，但益生菌在胃肠道疾病治疗中的应用正在获得患者的认可。患者可能会参照将益生菌与更熟悉的治疗方式（包括补充和替代药物、药物治疗和基因转移技术）进行比较的解释框架，形成他们对益生菌治疗的态度和信念。这些框架都强调了关于益生菌使用的不同利益与风险考虑，并强化了益生菌治疗前景和危险的极端特征。可能需要相当大的努力来帮助患者对益生菌疗法做出明智的选择。
Applications of probiotics in the treatment of gastrointestinal disorders are gaining acceptance among patients, despite evidence that probiotics can present substantial health risks, particularly for patients who are immunocompromised or seriously ill. Patients will likely formulate their attitudes and beliefs about probiotic therapies with reference to interpretive frameworks that compare probiotics with more familiar therapeutic modalities, including complementary and alternative medicines, pharmacological therapies, and gene-transfer technologies. Each of these frameworks highlights a different set of benefit-to-risk considerations regarding probiotic usage and reinforces extreme characterizations of both the therapeutic promise and peril of probiotics. Considerable effort may be required to help patients make informed choices about probiotic therapies.
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24.5
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