Antiretroviral therapy adherence among transgender women living with HIV.
Antiretroviral therapy adherence among transgender women living with HIV.
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DOI：
10.1016/j.jana.2010.01.005
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发表时间：
2010-05
影响因子：
2
通讯作者：
Johnson, Mallory O.
中科院分区：
文献类型：
--
作者：
Sevelius, Jae M.;Carrico, Adam;Johnson, Mallory O.
尽管跨性别女性的艾滋病毒感染率不成比例，并且有证据表明坚持用药对于治疗成功和增加生存可能性至关重要，但对跨性别女性抗逆转录病毒治疗（ART）依从性问题的调查却很少。这项研究调查了接受 ART 的跨性别女性 (n = 35) 中自我报告的 ART 依从率，以及与其他受访者 (n = 2,770) 相比，不依从的既定相关因素，包括抑郁、依从自我效能、患者对与其提供者互动的看法以及感知到的 ART 不良副作用。接受 ART 的跨性别女性不太可能达到 90% 或更高的依从率，并且对自己将治疗方案融入日常生活的能力缺乏信心。当跨性别女性与其他受访者进行比较时，无论当前的药物治疗方案如何，她们与医疗保健提供者的积极互动明显较少。建议对提供者进行培训并将激素治疗纳入艾滋病毒护理中。
Despite disproportionate rates of HIV among transgender women and evidence that medication adherence is necessary for treatment success and increased likelihood of survival, there has been little investigation into antiretroviral treatment (ART) adherence issues among transgender women. This study examined rates of self-reported ART adherence among transgender women on ART (n = 35) and well-established correlates of nonadherence including depression, adherence self-efficacy, patient perceptions of interactions with their providers, and perceived adverse side effects of ART compared to other respondents (n = 2,770). Transgender women on ART were less likely to report 90% adherence rates or higher and reported less confidence in their abilities to integrate treatment regimens into their daily lives. When transgender women were compared to other respondents, regardless of the current medication regimen, they reported significantly fewer positive interactions with their health care providers. Training for providers and integration of hormone therapy into HIV care is recommended.
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