Short-Term Air Pollution Exposure and Risk of Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Korea: A National Time-Stratified Case-Crossover Study.
Short-Term Air Pollution Exposure and Risk of Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Korea: A National Time-Stratified Case-Crossover Study.
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DOI：
10.3390/ijerph19052823
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发表时间：
2022-02-28
影响因子：
--
通讯作者：
Ha KH
中科院分区：
文献类型：
--
作者：
Jung YJ;Kim EJ;Heo JY;Choi YH;Kim DJ;Ha KH
我们调查了韩国七个大城市的短期空气污染暴露与慢性阻塞性肺疾病 (AE-COPD) 急性加重风险之间的关联。我们使用国民健康保险理赔数据来识别2015年AE-COPD病例。我们估算了从环境部获得的直径≤2.5微米的颗粒物（PM2.5）、直径≤10微米的颗粒物（PM10）、二氧化硫（SO2）、二氧化氮（NO2）、一氧化碳（CO）和臭氧（O3）的短期暴露情况。我们进行了一项时间分层、病例交叉研究，使用条件逻辑回归模型评估短期暴露于空气污染对 AE-COPD 就诊的影响。在累积滞后模型中，AE-COPD 就诊的风险与 PM10 四分位间距的增加显着相关（滞后 0-2，0.35%，95% 置信区间 (CI) 0.06-0.65%；滞后 0-3，0.39%，95% CI 0.01-0.77%）。在年龄 40-64 岁、家庭收入低且有哮喘病史的男性患者中，这种相关性更高。然而，其他空气污染物与 AE-COPD 就诊的风险没有显着相关性。短期暴露于空气污染，尤其是 PM10，会增加因 AE-COPD 住院的风险。
We investigated the association between short-term exposure to air pollution and the risk of acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) in seven metropolitan cities in Korea. We used national health insurance claims data to identify AE-COPD cases in 2015. We estimated short-term exposure to particulate matter (PM) with a diameter of ≤2.5 μm (PM2.5), PM with diameters of ≤10 μm (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone (O3) obtained from the Ministry of Environment. We conducted a time-stratified, case-crossover study to evaluate the effect of short-term exposure to air pollution on hospital visits for AE-COPD, using a conditional logistic regression model. The risk of hospital visits for AE-COPD was significantly associated with interquartile range increases in PM10 in a cumulative lag model (lag 0–2, 0.35%, 95% confidence interval (CI) 0.06–0.65%; lag 0–3, 0.39%, 95% CI 0.01–0.77%). The associations were higher among patients who were men, aged 40–64 years, with low household income, and with a history of asthma. However, other air pollutants were not significantly associated with the risk of hospital visits for AE-COPD. Short-term exposure to air pollution, especially PM10, increases the risk of hospital visits for AE-COPD.
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DOI：
10.2147/copd.s54417
发表时间：
2014
影响因子：
2.8
作者：
Punekar YS;Shukla A;Müllerova H
通讯作者：
Müllerova H
影响因子：
7.7
作者：
Lee, Juneyoung;Lee, Ji Sung;Kim, KeeWhan
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DOI：
10.1007/s40201-021-00709-7
发表时间：
2021-07-15
影响因子：
3.4
作者：
Han, Chang Hoon;Pak, Haeyong;Chung, Jae Ho
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Chung, Jae Ho
DOI：
10.2147/copd.s48577
发表时间：
2013
影响因子：
2.8
作者：
Kim J;Rhee CK;Yoo KH;Kim YS;Lee SW;Park YB;Lee JH;Oh Y;Lee SD;Kim Y;Kim K;Yoon H
通讯作者：
Yoon H
DOI：
10.3109/15412555.2013.831061
发表时间：
2014-04-01
影响因子：
2.2
作者：
Rhee, Chin Kook;Yoon, Hyoung Kyu;Lee, Sang Do
通讯作者：
Lee, Sang Do