Compliance with and acceptability of two fortified balanced energy protein supplements among pregnant women in rural Nepal.
Compliance with and acceptability of two fortified balanced energy protein supplements among pregnant women in rural Nepal.
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DOI：
10.1111/mcn.13306
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发表时间：
2022-04
影响因子：
3.4
通讯作者：
Tielsch JM
中科院分区：
文献类型：
--
作者：
Lama TP;Moore K;Isanaka S;Jones L;Bedford J;de Pee S;Katz J;Khatry SK;LeClerq SC;Tielsch JM
一些证据表明，怀孕和哺乳期间服用平衡能量蛋白（BEP）补充剂可以对出生结局产生积极影响，例如小于胎龄和出生体重，但需要更多证据来证明此类补充剂的长期使用和可接受性。我们进行了一项混合方法形成性研究，以评估和比较两种 BEP 补充剂（一种脂基花生酱和一种饼干）的依从性和可接受性，以确定 BEP 补充剂，以便随后纳入功效试验。我们在尼泊尔农村地区的两组孕妇中进行了一项为期 8 周的每日补充补充剂的喂养试验，每组 40 名孕妇。收集依从性数据并在每周访问时分发补充材料。使用 7 点李克特量表评估补充剂的感官特性。此外，还对妇女（n = 16）、家庭成员（n = 6）和卫生工作者（n = 6）进行了深入访谈，并进行焦点小组讨论（FGD）（n = 4），以探讨与补充剂的一般使用和未来使用意图相关的主题。总体自我报告的依从性很高：脂质花生酱组的中位数为 91.1%，饼干组的中位数为 96.4%。这两种补充剂在整体喜爱度（中位数 6/7）和感官特性方面均获得很高评价。定性研究结果表明，持续使用补充剂归因于预期的健康益处、良好的感官特性和家庭支持。 FGD 建议提供在多种类型/口味的补充剂之间进行选择的选项，以提高依从性。第一周的分享最为明显，饼干组的分享量更高。在为期 8 周的家庭喂养试验中，脂基花生酱和香草饼干都受到尼泊尔农村孕妇的广泛接受。依从性测量显示，两个补充剂组的总体依从性很高，原因是对母亲和婴儿的健康益处、良好的感官特性、有利于产品消费的家庭环境（隐私和家庭支持）以及产品使用的便利性。在对营养食品补充剂进行功效试验之前，重要的是在研究人群中进行混合方法喂养试验，以了解启用和阻止使用补充剂的背景因素，从而了解提高补充剂依从性的方法。
Some evidence suggests that balanced energy protein (BEP) supplements taken during pregnancy and lactation can have positive effects on birth outcomes such as small‐for‐gestational age and birthweight, but more evidence is needed on the long‐term use and acceptability of such supplements. We conducted a mixed‐methods formative research study to assess and compare compliance with and acceptability of two BEP supplements, a lipid‐based peanut paste and a biscuit, to identify BEP supplements for subsequent inclusion in an efficacy trial. We conducted an 8‐week feeding trial of daily supplementation among two groups of 40 pregnant women each in rural Nepal. Compliance data were collected and supplements distributed at the weekly visits. Sensory properties of the supplements were assessed using a 7‐point Likert scale. In addition, in‐depth interviews with women (n = 16), family members (n = 6) and health workers (n = 6) and focus group discussions (FGDs) (n = 4) were conducted to explore themes related to general use and intention of future use of the supplement. Overall self‐reported compliance was high: medians of 91.1% in the lipid‐based peanut paste group and 96.4% in the biscuit group. Both supplements were rated highly on overall likability (median score 6/7) and sensory properties. Qualitative findings showed that sustained use of the supplements was attributed to expected health benefits, favourable sensory attributes, and family support. The FGDs suggested providing the option to choose between more than one type/flavour of supplements to improve compliance. Sharing was mostly evident in the first week with higher sharing reported in the biscuit group. Both the lipid‐based peanut paste and the vanilla biscuit were well accepted by pregnant women in rural Nepal during an 8‐week home feeding trial. The compliance measurements showed high overall compliance in both supplement groups with the reasons being the perceived health benefits to the mother and baby, favourable sensory properties, enabling environment at home for product consumption (privacy and family support) and ease of product use. Before an efficacy trial of a nutritional food supplement, it is important to conduct a mixed‐methods feeding trial in the study population to understand the contextual factors that enable and prevent the use of supplements to inform ways to improve compliance with the supplements.
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影响因子：
1.9
作者：
Fall CH;Fisher DJ;Osmond C;Margetts BM;Maternal Micronutrient Supplementation Study Group
通讯作者：
Maternal Micronutrient Supplementation Study Group
影响因子：
5.4
作者：
Iuel-Brockdorf, Ann-Sophie;Draebel, Tania Aase;Friis, Henrik
通讯作者：
Friis, Henrik
影响因子：
3.4
作者：
Adu-Afarwuah, Seth;Lartey, Anna;Dewey, Kathryn G.
通讯作者：
Dewey, Kathryn G.
影响因子：
4.2
作者：
Jiang, TN;Christian, P;West, KP
通讯作者：
West, KP
影响因子：
7.7
作者：
Christian P;Lee SE;Donahue Angel M;Adair LS;Arifeen SE;Ashorn P;Barros FC;Fall CH;Fawzi WW;Hao W;Hu G;Humphrey JH;Huybregts L;Joglekar CV;Kariuki SK;Kolsteren P;Krishnaveni GV;Liu E;Martorell R;Osrin D;Persson LA;Ramakrishnan U;Richter L;Roberfroid D;Sania A;Ter Kuile FO;Tielsch J;Victora CG;Yajnik CS;Yan H;Zeng L;Black RE
通讯作者：
Black RE