Halving imaging time of whole brain diffusion spectrum imaging and diffusion tractography using simultaneous image refocusing in EPI.

Halving imaging time of whole brain diffusion spectrum imaging and diffusion tractography using simultaneous image refocusing in EPI.
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DOI:
10.1002/jmri.21497
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发表时间:
2009-03
影响因子:
4.4
通讯作者:
Wedeen, Van J.
Wedeen, Van J.
中科院分区:
医学2区
文献类型:
--
作者:
Reese, Timothy G.;Benner, Thomas;Wang, Ruopeng;Feinberg, David A.;Wedeen, Van J.

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为了提高大脑密集编码扩散成像(例如扩散频谱成像(DSI))的效率,我们使用同步图像重聚焦回波平面成像(SIR-EPI)在同一读数中对多个切片进行时间复用。总扫描时间的低效率是由于扩散编码梯度脉冲的时间过长造成的,该扩散编码梯度脉冲必须对每个图像重复进行。我们提出了一种高效的多路复用方法,即同时图像重聚焦(SIR),可将扩散成像的总扫描时间减少近一半。 SIR DSI 在 10 分钟内完成,而不是 21 分钟,对于常规临床应用来说是可以接受的。完成了两项相同的研究,比较了传统的单层回波平面 (EPI) DSI 和同时图像重聚焦 (SIR-EPI) DSI,显示出相同的 SNR 和对比度以及配准方面的微小差异,这可能是由于典型的受试者运动所致。 DSI 和 DTI 纤维束描记器的比较显示白质纤维束的质量和检测相匹配。 SIR-EPI 中扩散编码梯度脉冲数量净减少近一半,显着减少了 DSI 和 DTI 的采集时间。
To increase the efficiency of densely encoded diffusion imaging of the brain, such as diffusion spectrum imaging (DSI), we time-multiplex multiple slices within the same readout using simultaneous image refocusing echo planar imaging (SIR-EPI). Inefficiency in total scan time results from the long time of diffusion encoding gradient pulses which must be repeated for each and every image. We present a highly efficient multiplexing method, simultaneous image refocusing (SIR) for reducing the total scan time of diffusion imaging by nearly one-half. SIR DSI is performed in 10 minutes rather than 21 minutes, acceptable for routine clinical application. Two identical studies were completed, comparing conventional single-slice echo-planar (EPI) DSI and simultaneous image refocusing (SIR-EPI) DSI, showing equal SNR and contrast and small differences in registration, likely due to typical subject motion. Comparison of DSI and DTI tractographs showed matching quality and detection of white matter tracts. The net reduction to nearly half the number of diffusion encoding gradient pulses in SIR-EPI significantly reduces acquisition times of DSI and DTI.
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发表时间: 1994-03-01
期刊: JOURNAL OF MAGNETIC RESONANCE SERIES B
影响因子: --
作者:
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