Effect of salidroside on learning and memory ability of vascular dementia rats
Effect of salidroside on learning and memory ability of vascular dementia rats
复制标题
红景天苷对血管性痴呆大鼠学习记忆能力的影响
DOI:
10.5897/ajpp11.825
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发表时间:
2012-01
影响因子:
--
通讯作者:
Teng, Junfang
中科院分区:
文献类型:
--
作者:
Deng, Wenjing;Lu, Hong;Ren, Xinwei;Teng, Junfang
The effect of salidroside (SD) on learning and memory ability of vascular dementia (VaD) rats were studied. The Wistar rats were randomly divided into six groups: Sham-operation group, VaD group, positive control (PC) group, SD high dose (SD-HD) treatment group, SD moderate dose (SD-MD) treatment group and SD low dose (SD-LD) treatment group. The bilateral common carotid arteries of Wistar rats were permanently ligated to established VaD models. The special study and memory were observed by Y-maze test. At postoperative 4, 8 and 12 weeks, error number (EN) and total reaction time (TRT) in the VaD, PC, SD-HD, SD-MD and SD-LD group were significantly more than those in the sham- operation group (P 0.05). These results suggested that SD could improve the learning and memory ability of VaD rats by different dosages.
Key words: Salidroside, vascular dementia, rats.
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影响因子:
2
作者:
I. Mook-Jung;H. Kim;W. Fan;Y. Tezuka;S. Kadota;H. Nishijo;M. Jung
通讯作者:
I. Mook-Jung;H. Kim;W. Fan;Y. Tezuka;S. Kadota;H. Nishijo;M. Jung
影响因子:
2.7
作者:
Lanza, AMD;Martínez, MJA;Benito, PB
通讯作者:
Benito, PB
DOI:
10.1007/978-0-387-30405-2
发表时间:
2007-07
期刊:
Handbook of Neurochemistry and Molecular Neurobiology
影响因子:
--
作者:
J. Hanoune
通讯作者:
J. Hanoune
DOI:
--
发表时间:
2001-06
期刊:
Alternative medicine review : a journal of clinical therapeutic
影响因子:
--
作者:
G. Kelly
通讯作者:
G. Kelly
DOI:
--
发表时间:
2002-11
期刊:
Eksperimental'naia i klinicheskaia farmakologiia
影响因子:
--
作者:
I. In;Grigor'eva Nf
通讯作者:
I. In;Grigor'eva Nf