Real-time primer design for DNA chips
Real-time primer design for DNA chips
复制标题
DNA 芯片实时引物设计
DOI:
10.1109/ipdps.2003.1213288
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发表时间:
2003
期刊:
影响因子:
--
通讯作者:
R. Männer
中科院分区:
文献类型:
--
作者:
H. Simmler;H. Singpiel;R. Männer
The design of PCR or DNA chip experiments is a time consuming process where bioinformatics is extensively used. The selection of the primers, which are immobilized on the DNA chip, requires a complex algorithm. Based on several parameters an optimized set of primers is automatically detected for a given gene sequence. This paper describes a parallel architecture which performs the optimization of the primer selection on a hardware accelerator. In contrast to the pure software approach, the parallel architecture gains a speedup of factor 500 using a PCI based hardware accelerator. This approach allows an optimization of a specified primer set in real-time.
DOI:
10.1073/pnas.83.24.9373
发表时间:
1986-12-01
影响因子:
11.1
作者:
FREIER, SM;KIERZEK, R;TURNER, DH
通讯作者:
TURNER, DH
DOI:
10.1073/pnas.83.11.3746
发表时间:
1986-06-01
影响因子:
11.1
作者:
BRESLAUER, KJ;FRANK, R;MARKY, LA
通讯作者:
MARKY, LA