Perception of better nasal patency correlates with increased mucosal cooling after surgery for nasal obstruction.
Perception of better nasal patency correlates with increased mucosal cooling after surgery for nasal obstruction.
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DOI：
10.1177/0194599813509776
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发表时间：
2014-01
期刊：
影响因子：
--
通讯作者：
Rhee JS
中科院分区：
文献类型：
--
作者：
Sullivan CD;Garcia GJ;Frank-Ito DO;Kimbell JS;Rhee JS
1.量化粘膜冷却（即，使用计算流体动力学（CFD）在手术之前和之后在鼻气道阻塞（NAO）患者的鼻通道中的空间热损失）。2.将粘膜冷却与患者报告的症状相关联，通过鼻塞症状评价（NOSE）和鼻气流感觉的视觉模拟量表（VAS）进行测量。未来的学术三级医疗中心。10例患者在手术前和手术后进行计算机断层扫描（CT）扫描和NOSE和VAS调查，以缓解NAO。每个病人的鼻腔解剖结构的三维模型被用来运行在吸气期间的气流和热传递的稳态CFD模拟。比较术前和术后鼻前庭和整个鼻腔的热损失以及暴露于> 50 W/m2热通量的粘膜表面积。手术后，术前最阻塞侧的热损失显著增加（p值< 0.0002）。手术后鼻粘膜的较大表面积暴露于> 50 W/m2的热通量。对于热通量> 50 W/m2（Pearson r =-0.76）的表面积，NOSE获得了患者报告的鼻通畅性与CFD测量值之间的最佳相关性。术后粘膜冷却的显著增加与NAO手术后患者对更好的鼻通畅性的感知密切相关。CFD导出的热通量可能被证明是NAO手术成功的有价值的预测因素。
1. Quantify mucosal cooling (i.e., heat loss) spatially in the nasal passages of nasal airway obstruction (NAO) patients before and after surgery using computational fluid dynamics (CFD). 2. Correlate mucosal cooling with patient-reported symptoms, as measured by the Nasal Obstruction Symptom Evaluation (NOSE) and a visual analog scale (VAS) for sensation of nasal airflow. Prospective Academic tertiary medical center. Computed tomography (CT) scans and NOSE and VAS surveys were obtained from 10 patients before and after surgery to relieve NAO. Three-dimensional models of each patient’s nasal anatomy were used to run steady-state CFD simulations of airflow and heat transfer during inspiration. Heat loss across the nasal vestibule and the entire nasal cavity, and the surface area of mucosa exposed to heat fluxes > 50 W/m2 were compared pre- and post-operatively. After surgery, heat loss increased significantly on the pre-operative most obstructed side (p values < 0.0002). A larger surface area of nasal mucosa was exposed to heat fluxes > 50 W/m2 after surgery. The best correlation between patient-reported and CFD measures of nasal patency was obtained for NOSE against surface area in which heat fluxes > 50 W/m2 (Pearson r = −0.76). A significant post-operative increase in mucosal cooling correlates well with patients’ perception of better nasal patency after NAO surgery. CFD-derived heat fluxes may prove to be a valuable predictor of success in NAO surgery.
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影响因子：
2.6
作者：
Illum, P
通讯作者：
Illum, P
影响因子：
1.7
作者：
JONES, AS;WILLATT, DJ;DURHAM, LM
通讯作者：
DURHAM, LM
影响因子：
1.7
作者：
FJERMEDAL, O;SAUNTE, C;PEDERSEN, S
通讯作者：
PEDERSEN, S
DOI：
10.1159/000275761
发表时间：
1985-01-01
期刊：
ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES
影响因子：
--
作者：
DOMMERBY, H;RASMUSSEN, OR;ROSBORG, J
通讯作者：
ROSBORG, J
影响因子：
2.1
作者：
JONES, AS;CROSHER, R;BECKINGHAM, E
通讯作者：
BECKINGHAM, E