A meta-analysis of acupuncture combined with opioid receptor agonists for treatment of opiate-withdrawal symptoms.
A meta-analysis of acupuncture combined with opioid receptor agonists for treatment of opiate-withdrawal symptoms.
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DOI：
10.1007/s10571-008-9336-4
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发表时间：
2009-06
影响因子：
4
通讯作者：
Lu, Lin
中科院分区：
文献类型：
--
作者：
Liu, Ting-ting;Shi, Jie;Epstein, David H.;Bao, Yan-ping;Lu, Lin
This review extends a prior meta-analysis of acupuncture’s utility for treating opioid detoxification, addressing the efficacy of acupuncture when combined with allopathic therapies. Both English and Chinese databases were searched for randomized trials comparing acupuncture combined with opioid agonist treatment versus opioid agonists alone for treating symptoms of opioid withdrawal. The methodological quality of each study was assessed with Jadad’s scale (1–2 = low; 3–5 = high). Meta-analysis was performed with fixed- or random-effect models in RevMan software; the outcome measures assessed were withdrawal-symptoms score, relapse rate, side effects, and medication dosage. Withdrawal-symptom scores were lower in combined treatment trials than in agonist-alone trials on withdrawal days 1, 7, 9, and 10. Combined treatment also produced lower reported rates of side effects and appeared to lower the required dose of opioid agonist. There was no significant difference on relapse rate after 6 months. This meta-analysis suggests that acupuncture combined with opioid agonists can effectively be used to manage the withdrawal symptoms. One limitation of this meta-analysis is the poor quality of the methodology of some included trials. High-quality studies are needed to confirm findings regarding the side effects and medication dosage.
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影响因子：
22.4
作者：
ROSENTHAL, R
通讯作者：
ROSENTHAL, R
影响因子：
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作者：
Avants, SK;Margolin, A;Kosten, TR
通讯作者：
Kosten, TR
影响因子：
120.7
作者：
Margolin, A;Kleber, HD;Vaughan, R
通讯作者：
Vaughan, R
DOI：
10.1142/s0147291777000362
发表时间：
1977-01-01
期刊：
COMPARATIVE MEDICINE EAST AND WEST
影响因子：
--
作者：
WEN, HL
通讯作者：
WEN, HL
DOI：
10.1016/0197-2456(95)00134-4
发表时间：
1996-02-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
Jadad, AR;Moore, RA;McQuay, HJ
通讯作者：
McQuay, HJ