Serum immunoglobulin G antibody subclass responses to respiratory syncytial virus F and G glycoproteins after primary infection

Serum immunoglobulin G antibody subclass responses to respiratory syncytial virus F and G glycoproteins after primary infection
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原发感染后血清免疫球蛋白G抗体亚类对呼吸道合胞病毒F和G糖蛋白的反应

DOI:
10.1128/jcm.24.2.304-306.1986
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发表时间:
1986
影响因子:
9.4
通讯作者:
B. Murphy
B. Murphy
中科院分区:
医学2区
文献类型:
--
作者:
D. Wagner;B. Graham;P. Wright;E. Walsh;H. W. Kim;C. B. Reimer;D. Nelson;R. Chanock;B. Murphy

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由于免疫球蛋白G (IgG)对碳水化合物抗原的反应通常来自IgG2亚类,而IgG对蛋白质抗原的反应通常来自IgG1,有时也来自IgG3亚类,两种呼吸道合胞病毒糖蛋白F和G在糖基化量上有很大差异,作为酶联免疫吸附试验的抗原,测定20例自然获得性呼吸道合胞病毒感染婴幼儿的IgG亚类反应。这两种糖蛋白主要引起IgG1和IgG3反应,表明糖蛋白的蛋白质部分可能在该年龄组中具有免疫优势。
Because the immunoglobulin G (IgG) response to carbohydrate antigens is typically from the IgG2 subclass and the IgG response to protein antigens is typically from the IgG1 and sometimes the IgG3 subclass, two respiratory syncytial virus glycoproteins, F and G, which differ substantially in the amount of glycosylation, were used as antigens in an enzyme-linked immunosorbent assay to determine IgG subclass responses in 20 infants and young children with naturally acquired respiratory syncytial virus infection. Both glycoproteins elicited primarily IgG1 and IgG3 responses, indicating that the protein moieties of the glycoproteins may be immunodominant in this age group.
单纯疱疹病毒的 IgG 亚类抗体。
DOI: 10.1093/infdis/151.5.929
发表时间: 1985
期刊: The Journal of infectious diseases
影响因子: --
作者:
Coleman,RM;Nahmias,AJ;Williams,SC;Phillips,DJ;Black,CM;Reimer,CB
通讯作者: Reimer,CB
DOI: 10.1073/pnas.81.24.7683
发表时间: 1984-01-01
期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子: --
作者:
COLLINS, PL;HUANG, YT;WERTZ, GW
通讯作者: WERTZ, GW
DOI: 10.1073/pnas.82.12.4075
发表时间: 1985-06
影响因子: 11.1
作者:
G. Wertz;P. Collins;Yung;Huang;C. Gruber;S. Levine;L. Ball
通讯作者: G. Wertz;P. Collins;Yung;Huang;C. Gruber;S. Levine;L. Ball