Reconfiguration of brain networks supporting inhibition of emotional challenge.
Reconfiguration of brain networks supporting inhibition of emotional challenge.
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DOI：
10.1016/j.neuroimage.2018.10.066
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发表时间：
2019-02-01
期刊：
影响因子：
5.7
通讯作者：
Spielberg JM
中科院分区：
文献类型：
--
作者：
Bartholomew ME;Yee CM;Heller W;Miller GA;Spielberg JM
对刺激的显著情绪特征的反应是适应性的，除非信息无关或干扰目标导向的行为。忽略重要但无关的信息的能力涉及大脑网络的重组，是几种心理障碍的关键缺陷。尽管理解情绪反应的抑制性控制很重要，但相关的大脑网络机制仍然未知。本研究利用从103名执行情绪词Stroop （EWS）任务的参与者获得的功能磁共振成像（fMRI）数据，应用图论分析来确定在成功抑制情绪干扰物的反应过程中，负责情绪处理和认知控制的大脑区域如何在全球大脑网络中整合，以促进更专业化和更有效的处理。目前的研究确定了两个与情绪抑制相关的子网络，一个涉及前额叶皮层的超连接，另一个涉及丘脑的超连接。通常与识别情绪显著性相关的大脑区域与丘脑中枢的联系更为紧密，这与丘脑放大前额叶皮层对这些区域的控制一致。此外，高情绪唤醒刺激促进了全球网络的重组，以提高集群处理和整体沟通效率。这些结果证明情绪抑制依赖于认知控制和情绪突出子网络之间的相互作用。
Reacting to the salient emotional features of a stimulus is adaptive unless the information is irrelevant or interferes with goal-directed behavior. The ability to ignore salient but otherwise extraneous information involves restructuring of brain networks and is a key impairment in several psychological disorders. Despite the importance of understanding inhibitory control of emotional response, the associated brain network mechanisms remain unknown. Utilizing functional magnetic resonance imaging (fMRI) data obtained from 103 participants performing an emotion-word Stroop (EWS) task, the present study applied graph-theory analysis to identify how brain regions subserving emotion processing and cognitive control are integrated within the global brain network to promote more specialized and efficient processing during successful inhibition of response to emotional distractors. The present study identified two sub-networks associated with emotion inhibition, one involving hyper-connectivity to prefrontal cortex and one involving hyper-connectivity to thalamus. Brain regions typically associated with identifying emotion salience were more densely connected with the thalamic hub, consistent with thalamic amplification of prefrontal cortex control of these regions. Additionally, stimuli high in emotion arousal prompted restructuring of the global network to increase clustered processing and overall communication efficiency. These results provide evidence that inhibition of emotion relies on interactions between cognitive control and emotion salience sub-networks.
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影响因子：
1.9
作者：
Canli, T;Zhao, Z;Gabrieli, JDE
通讯作者：
Gabrieli, JDE
皮质连通性的丘脑扩增可维持注意力控制。
影响因子：
64.8
作者：
Schmitt LI;Wimmer RD;Nakajima M;Happ M;Mofakham S;Halassa MM
通讯作者：
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影响因子：
4.6
作者：
MACLEOD, C;MATHEWS, A;TATA, P
通讯作者：
TATA, P
影响因子：
2.9
作者：
Compton, Rebecca J.;Banich, Marie T.;Heller, Wendy
通讯作者：
Heller, Wendy
影响因子：
5.3
作者：
Beauregard, M;Lévesque, J;Bourgouin, P
通讯作者：
Bourgouin, P