Role of PET to evaluate coronary microvascular dysfunction in non-ischemic cardiomyopathies.
Role of PET to evaluate coronary microvascular dysfunction in non-ischemic cardiomyopathies.
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DOI:
10.1007/s10741-017-9628-1
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发表时间:
2017-07
影响因子:
4.6
通讯作者:
Dorbala S
中科院分区:
文献类型:
--
作者:
Bravo PE;Di Carli MF;Dorbala S
Coronary microvascular dysfunction (CMD) can result from structural and functional abnormalities at the intramural and small coronary vessel level affecting coronary blood flow autoregulation, and consequently leading to impaired coronary flow reserve. CMD often co-exists with epicardial coronary artery disease, but is also commonly seen in patients with various forms of heart disease, including dilated, hypertrophic and infiltrative cardiomyopathies. CMD can go unnoticed without any symptoms, or manifest as angina, and/or dyspnea, and contribute to the development of heart failure, and even sudden death especially when co-existing with myocardial fibrosis. However, whether CMD in non-ischemic cardiomyopathy is a cause or an effect of the underlying cardiomyopathic process, or whether it can be potentially modifiable with specific therapies, remains incompletely understood.
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DOI:
10.1152/ajpheart.00503.2011
发表时间:
2011-12-01
影响因子:
4.8
作者:
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通讯作者:
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DOI:
10.1016/j.jchf.2014.03.009
发表时间:
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期刊:
JACC. Heart failure
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作者:
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影响因子:
37.8
作者:
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影响因子:
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影响因子:
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作者:
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通讯作者:
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