Gestational diabetes mellitus: simplifying the international association of diabetes and pregnancy diagnostic algorithm using fasting plasma glucose.

Gestational diabetes mellitus: simplifying the international association of diabetes and pregnancy diagnostic algorithm using fasting plasma glucose.
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DOI:
10.2337/dc10-0572
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发表时间:
2010-09
期刊:
影响因子:
16.2
通讯作者:
Shah SM
Shah SM
中科院分区:
医学1区
文献类型:
--
作者:
Agarwal MM;Dhatt GS;Shah SM

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确定国际糖尿病与妊娠协会研究组(IADPSG)标准对1)妊娠期糖尿病(GDM)诊断与美国糖尿病协会(ADA)标准的比较以及2)空腹血糖(FPG)预测GDM的影响。10283名孕妇接受75克口服葡萄糖耐量试验(OGTT)筛查GDM,使用两个FPG阈值(OGTT的)来判定和排除GDM。IADPSG和ADA标准分别在3875名(37.7%)女性和1328名(12.9%)女性中诊断为GDM (P < 0.0005)。在2975名(28.9%)女性中,FPG阈值≥5.1 mmol/l被诊断为GDM,特异性为100%,而在2228名(21.7%)女性中,FPG阈值<4.4 mmol/l被排除为GDM,敏感性为95.4%。5203例(50.6%)女性单独使用FPG可以避免OGTT。IADPSG标准使GDM患病率增加了近三倍。通过避开大量的ogtt,初始FPG可以大大简化IADPSG诊断算法。
To determine the impact of the International Association of Diabetes and Pregnancy Study Group (IADPSG) criteria on 1) gestational diabetes mellitus (GDM) diagnosis compared with the American Diabetes Association (ADA) criteria and 2) the fasting plasma glucose (FPG) to predict GDM. In 10,283 pregnant women undergoing a 75-g oral glucose tolerance test (OGTT) for universal screening of GDM, two FPG thresholds (of the OGTT) were used to rule in and to rule out GDM. The IADPSG and ADA criteria identified GDM in 3,875 (37.7%) women and 1,328 (12.9%) women, respectively (P < 0.0005). FPG thresholds of ≥5.1 mmol/l ruled in GDM in 2,975 (28.9%) women with 100% specificity, while <4.4 mmol/l ruled out GDM in 2,228 (21.7%) women with 95.4% sensitivity. FPG independently could have avoided the OGTT in 5,203 (50.6%) women. The IADPSG criteria increased GDM prevalence nearly threefold. By circumventing a significant number of OGTTs, an initial FPG can greatly simplify the IADPSG diagnostic algorithm.
DOI: 10.1007/978-1-84882-120-0_3
发表时间: 2010-01-01
期刊: GESTATIONAL DIABETES DURING AND AFTER PREGNANCY
影响因子: --
作者:
Agarwal, Mukesh
通讯作者: Agarwal, Mukesh
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通讯作者: Evidence-Based Laboratory Medicine Committee of the American Association for Clinical Chemistry
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DOI: 10.1016/j.ejogrb.2004.07.034
发表时间: 2005-05-01
影响因子: 2.6
作者:
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通讯作者: Koster, G
DOI: 10.1111/j.1464-5491.2005.01706.x
发表时间: 2005-12-01
期刊: DIABETIC MEDICINE
影响因子: 3.5
作者:
Agarwal, MM;Dhatt, GS;Koster, G
通讯作者: Koster, G