Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.
Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.
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DOI：
10.2337/dc11-9998
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发表时间：
2011-06
期刊：
影响因子：
16.2
通讯作者：
Evidence-Based Laboratory Medicine Committee of the American Association for Clinical Chemistry
中科院分区：
文献类型：
--
作者：
Sacks DB;Arnold M;Bakris GL;Bruns DE;Horvath AR;Kirkman MS;Lernmark A;Metzger BE;Nathan DM;National Academy of Clinical Biochemistry;Evidence-Based Laboratory Medicine Committee of the American Association for Clinical Chemistry
多种实验室检测用于糖尿病患者的诊断和治疗。支持使用这些检测的科学证据质量差异很大。
一个专家委员会为糖尿病患者的实验室检测使用编写了基于证据的建议。开发了一种新的系统来对证据的总体质量和建议的强度进行分级。指南草案发布在互联网上，并在2007年阿诺德·O·贝克曼会议上展示。该文件根据口头和书面意见进行了修改，修订草案于2010年发布，并再次根据书面意见进行修改。美国临床生物化学学会和美国临床化学协会的循证实验室医学委员会共同审查了这些指南，经专业实践委员会修订后被接受，随后得到美国糖尿病协会执行委员会的批准。
除了基于血浆葡萄糖测量的长期标准外，还可通过显示血液中糖化血红蛋白（HbA1c）浓度升高来诊断糖尿病。通过血糖仪自我监测血浆或血糖以及对HbA1c进行实验室分析来监测血糖控制情况。文中还探讨了无创血糖监测、基因检测以及自身抗体、尿白蛋白、胰岛素、胰岛素原、C肽和其他分析物测量的潜在作用。
这些指南提供了基于已发表数据或源自专家共识的具体建议。目前有几种分析物临床价值极小，不建议对其进行检测。
Multiple laboratory tests are used to diagnose and manage patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these tests varies substantially. An expert committee compiled evidence-based recommendations for the use of laboratory testing for patients with diabetes. A new system was developed to grade the overall quality of the evidence and the strength of the recommendations. Draft guidelines were posted on the Internet and presented at the 2007 Arnold O. Beckman Conference. The document was modified in response to oral and written comments, and a revised draft was posted in 2010 and again modified in response to written comments. The National Academy of Clinical Biochemistry and the Evidence-Based Laboratory Medicine Committee of the American Association for Clinical Chemistry jointly reviewed the guidelines, which were accepted after revisions by the Professional Practice Committee and subsequently approved by the Executive Committee of the American Diabetes Association. In addition to long-standing criteria based on measurement of plasma glucose, diabetes can be diagnosed by demonstrating increased blood hemoglobin A1c (HbA1c) concentrations. Monitoring of glycemic control is performed by self-monitoring of plasma or blood glucose with meters and by laboratory analysis of HbA1c. The potential roles of noninvasive glucose monitoring, genetic testing, and measurement of autoantibodies, urine albumin, insulin, proinsulin, C-peptide, and other analytes are addressed. The guidelines provide specific recommendations that are based on published data or derived from expert consensus. Several analytes have minimal clinical value at present, and their measurement is not recommended.
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影响因子：
7.7
作者：
Arnold, MA
通讯作者：
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