Valproate-Induced Epigenetic Upregulation of Hypothalamic Fto Expression Potentially Linked with Weight Gain
Valproate-Induced Epigenetic Upregulation of Hypothalamic Fto Expression Potentially Linked with Weight Gain
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丙戊酸诱导的下丘脑 Fto 表达表观遗传上调可能与体重增加相关
DOI:
10.1007/s10571-020-00895-2
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发表时间:
2020-06
影响因子:
4
通讯作者:
Long Yue-Sheng
中科院分区:
文献类型:
--
作者:
Zhang Huan;Lu Ping;Tang Hui-Ling;Yan Hua-Juan;Jiang Wei;Shi Hang;Chen Si-Yu;Gao Mei-Mei;Zeng Xiang-Da;Long Yue-Sheng
Valproate (VPA), a widely-used antiepileptic drug, is a selective inhibitor of histone deacetylase (HDAC) that play important roles in epigenetic regulation. The patient with different diseases receiving this drug tend to exhibit weight gain and abnormal
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