Crossmodal Processing of Haptic Inputs in Sighted and Blind Individuals
Crossmodal Processing of Haptic Inputs in Sighted and Blind Individuals
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明眼人和盲人触觉输入的跨模态处理
DOI：
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发表时间：
2016
影响因子：
3
通讯作者：
F. Lepore
中科院分区：
文献类型：
--
作者：
P. Voss;F. Alary;L. Lazzouni;C. Chapman;R. Goldstein;Pierre Bourgoin;F. Lepore
在以前的行为研究中，它表明，早期失明的个人是上级的区别二维（2D）的触觉角度刺激。本研究的目的是评估神经基板与触觉二维角度辨别任务在视力和盲人。受试者进行触觉角度大小的歧视，以调查是否跨模态枕叶招聘的模式是偏侧作为一个功能的刺激手。不同难度水平的任务诱发激活也进行了比较，以确定任务难度对枕区跨通道加工的潜在调节作用。我们发现，盲人受试者在执行触觉辨别任务时，右侧和上级枕回内有更广泛的激活。相反，在执行任务时，视力正常的人激活左侧楔叶和舌回的次数比盲人多。此外，视觉区域内的活动被证明是盲人触觉辨别阈值的预测，但不是在有视力的。顶叶和枕叶区域内的活动受到任务难度的调制，其中更容易的角度比较引起更多的枕叶活动沿着与双侧后顶叶活动，而更困难的比较产生更广泛的枕叶活动与减少顶叶激活相结合。最后，我们表明，跨模态重组内的枕叶皮层的盲人主要是右侧，无论刺激的手，支持以前的证据为右侧半球专业化的枕叶皮层的盲人的触觉和触觉输入的处理。
In a previous behavioral study, it was shown that early blind individuals were superior to sighted ones in discriminating two-dimensional (2D) tactile angle stimuli. The present study was designed to assess the neural substrate associated with a haptic 2D angle discrimination task in both sighted and blind individuals. Subjects performed tactile angle size discriminations in order to investigate whether the pattern of crossmodal occipital recruitment was lateralized as a function of the stimulated hand. Task-elicited activations were also compared across different difficulty levels to ascertain the potential modulatory role of task difficulty on crossmodal processing within occipital areas. We show that blind subjects had more widespread activation within the right lateral and superior occipital gyri when performing the haptic discrimination task. In contrast, the sighted activated the left cuneus and lingual gyrus more so than the blind when performing the task. Furthermore, activity within visual areas was shown to be predictive of tactile discrimination thresholds in the blind, but not in the sighted. Activity within parietal and occipital areas was modulated by task difficulty, where the easier angle comparison elicited more focal occipital activity along with bilateral posterior parietal activity, whereas the more difficult comparison produced more widespread occipital activity combined with reduced parietal activation. Finally, we show that crossmodal reorganization within the occipital cortex of blind individuals was primarily right lateralized, regardless of the stimulated hand, supporting previous evidence for a right-sided hemispheric specialization of the occipital cortex of blind individuals for the processing of tactile and haptic inputs.
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影响因子：
1.8
作者：
Stilla R;Hanna R;Hu X;Mariola E;Deshpande G;Sathian K
通讯作者：
Sathian K
影响因子：
2.5
作者：
Burton, H;Snyder, AZ;Raichle, ME
通讯作者：
Raichle, ME
影响因子：
2.8
作者：
Sathian K;Stilla R
通讯作者：
Stilla R
影响因子：
2.2
作者：
Sathian, K
通讯作者：
Sathian, K