Phantom acupuncture: dissociating somatosensory and cognitive/affective components of acupuncture stimulation with a novel form of placebo acupuncture.
Phantom acupuncture: dissociating somatosensory and cognitive/affective components of acupuncture stimulation with a novel form of placebo acupuncture.
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DOI：
10.1371/journal.pone.0104582
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Park K
中科院分区：
文献类型：
--
作者：
Lee J;Napadow V;Kim J;Lee S;Choi W;Kaptchuk TJ;Park K
在临床环境中，针灸治疗由多个组成部分组成，包括体感刺激、治疗背景和对针灸操作的关注。为了分离体感与背景和注意方面的针灸，我们设计了一种新的形式的安慰剂针灸，一种被称为幻影针灸的视觉操作，它再现了没有体感触觉刺激的针灸仪式。受试者(N = )20人同时接受真实(真实)和幻象(PHNT)针灸。根据PHNT的可信度，受试者被回顾地分为两组(PHNTc，认为幻象针灸可信；PHNTnc，不认为)。监测自主神经和心理生理反应。我们发现，PHNT可以以可信的方式交付。针刺是一种复杂的、仪式性的躯体感觉干预，它诱导交感神经激活(皮肤电导[SC]相反应)，这可能是针灸的体感成分所特有的。相反，背景效应，如针刺的可信度，反而与针刺过程中转向相对的心脏迷走神经激活(心率减慢)和针刺后的交感神经抑制(SC减少)和副交感神经激活(减小的瞳孔)有关。针刺仪式的视觉刺激是针刺时相自主神经反应的一个重要因素，并可能使针刺定向反应消失。我们的研究表明，幻象针灸可能是一种可行的假针灸对照，因为它完全排除了真实针刺的体感成分，同时在许多对象中保持了针灸治疗环境的可信度。
In a clinical setting, acupuncture treatment consists of multiple components including somatosensory stimulation, treatment context, and attention to needle-based procedures. In order to dissociate somatosensory versus contextual and attentional aspects of acupuncture, we devised a novel form of placebo acupuncture, a visual manipulation dubbed phantom acupuncture, which reproduces the acupuncture needling ritual without somatosensory tactile stimulation. Subjects (N = 20) received both real (REAL) and phantom (PHNT) acupuncture. Subjects were retrospectively classified into two groups based on PHNT credibility (PHNTc, who found phantom acupuncture credible; and PHNTnc, who did not). Autonomic and psychophysical responses were monitored. We found that PHNT can be delivered in a credible manner. Acupuncture needling, a complex, ritualistic somatosensory intervention, induces sympathetic activation (phasic skin conductance [SC] response), which may be specific to the somatosensory component of acupuncture. In contrast, contextual effects, such as needling credibility, are instead associated with a shift toward relative cardiovagal activation (decreased heart rate) during needling and sympathetic inhibition (decreased SC) and parasympathetic activation (decreased pupil size) following acupuncture needling. Visual stimulation characterizing the needling ritual is an important factor for phasic autonomic responses to acupuncture and may undelie the needling orienting response. Our study suggests that phantom acupuncture can be a viable sham control for acupuncture as it completely excludes the somatosensory component of real needling while maintaining the credibility of the acupuncture treatment context in many subjects.
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自然的选择性关注：定向和情感。
影响因子：
3.7
作者：
Bradley MM
通讯作者：
Bradley MM
影响因子：
2.7
作者：
Abercrombie, Heather C.;Chambers, Andrea S.;Monticelli, Roxanne M.
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影响因子：
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作者：
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通讯作者：
Dolan, RJ
影响因子：
2.6
作者：
Lang, Peter J.;Bradley, Margaret M.
通讯作者：
Bradley, Margaret M.
DOI：
10.1136/bmj.a3115
发表时间：
2009-01-27
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Madsen MV;Gøtzsche PC;Hróbjartsson A
通讯作者：
Hróbjartsson A