Data growth and its impact on the SCOP database: new developments.
Data growth and its impact on the SCOP database: new developments.
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DOI：
10.1093/nar/gkm993
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发表时间：
2008-01
影响因子：
14.9
通讯作者：
Murzin, Alexey G.
中科院分区：
文献类型：
--
作者：
Andreeva, Antonina;Howorth, Dave;Chandonia, John-Marc;Brenner, Steven E.;Hubbard, Tim J. P.;Chothia, Cyrus;Murzin, Alexey G.
蛋白质结构分类（SCOP）数据库是根据其进化和结构关系对所有已知结构的蛋白质进行的综合排序。SCOP层次结构包括以下级别：物种、蛋白质、家族、超家族、折叠和类别。在保持原始分类方案不变的同时，我们改变了SCOP的产生，以科普新结构数据的快速增长，并促进新蛋白质关系的发现。我们描述了正在进行的发展和新功能的SCOP。一个新的更新协议支持批分类的新的蛋白质结构，其检测到的关系，在家庭和超家庭的水平相比，我们以前的顺序处理新的结构数据的发布日期。我们介绍前SCOP，预览的SCOP开发版本，使更早地访问新的关系的信息。我们还讨论了全球结构基因组学计划的影响，这些计划正在以越来越快的速度产生新的蛋白质结构，对蛋白质家族和超家族的发现和增长率的影响。SCOP可以在http://scop.mrc-lmb.cam.ac.uk/scop上访问。
The Structural Classification of Proteins (SCOP) database is a comprehensive ordering of all proteins of known structure, according to their evolutionary and structural relationships. The SCOP hierarchy comprises the following levels: Species, Protein, Family, Superfamily, Fold and Class. While keeping the original classification scheme intact, we have changed the production of SCOP in order to cope with a rapid growth of new structural data and to facilitate the discovery of new protein relationships. We describe ongoing developments and new features implemented in SCOP. A new update protocol supports batch classification of new protein structures by their detected relationships at Family and Superfamily levels in contrast to our previous sequential handling of new structural data by release date. We introduce pre-SCOP, a preview of the SCOP developmental version that enables earlier access to the information on new relationships. We also discuss the impact of worldwide Structural Genomics initiatives, which are producing new protein structures at an increasing rate, on the rates of discovery and growth of protein families and superfamilies. SCOP can be accessed at http://scop.mrc-lmb.cam.ac.uk/scop.
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Pfam：氏族、网络工具和服务。
影响因子：
14.9
作者：
Finn, Robert D.;Mistry, Jaina;Schuster-Bockler, Benjamin;Griffiths-Jones, Sam;Hollich, Volker;Lassmann, Timo;Moxon, Simon;Marshall, Mhairi;Khanna, Ajay;Durbin, Richard;Eddy, Sean R.;Sonnhammer, Erik L. L.;Bateman, Alex
通讯作者：
Bateman, Alex
影响因子：
9.8
作者：
Yooseph S;Sutton G;Rusch DB;Halpern AL;Williamson SJ;Remington K;Eisen JA;Heidelberg KB;Manning G;Li W;Jaroszewski L;Cieplak P;Miller CS;Li H;Mashiyama ST;Joachimiak MP;van Belle C;Chandonia JM;Soergel DA;Zhai Y;Natarajan K;Lee S;Raphael BJ;Bafna V;Friedman R;Brenner SE;Godzik A;Eisenberg D;Dixon JE;Taylor SS;Strausberg RL;Frazier M;Venter JC
通讯作者：
Venter JC
影响因子：
14.9
作者：
Bairoch, Amos;Bougueleret, Lydie;Zhang, Jian
通讯作者：
Zhang, Jian
影响因子：
14.9
作者：
Andreeva, A;Howorth, D;Murzin, AG
通讯作者：
Murzin, AG
影响因子：
5.6
作者：
Moroz, OV;Murzin, AG;Galperin, MY
通讯作者：
Galperin, MY