Transgenic mice and squamous multistage skin carcinogenesis
Transgenic mice and squamous multistage skin carcinogenesis
复制标题
转基因小鼠和鳞状多阶段皮肤癌发生
DOI:
10.1007/bf00665795
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发表时间:
1995
影响因子:
9.2
通讯作者:
A. Balmain
中科院分区:
文献类型:
--
作者:
K. Brown;A. Balmain
The use of animals models of human cancers has proved useful in the elucidation of molecular events which occur during tumour development. Mouse skin has been used as a model for human squamous cancer for a number of decades, and analysis of this model has identified a number of changes important for the evolution of malignancy. Transgenic mice offer a further avenue of advancement, allowing refinement of the model, and the ability to examine the consequences of individual eventsin vivo in greater detail. This article reviews the impact of transgenic approaches to our understanding of multistage squamous carcinogenesis in mouse skin.
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DOI:
10.1111/1523-1747.ep12366045
发表时间:
1993
期刊:
The Journal of investigative dermatology
影响因子:
--
作者:
Miller,SJ;Wei,ZG;Wilson,C;Dzubow,L;Sun,TT;Lavker,RM
通讯作者:
Lavker,RM
影响因子:
11.2
作者:
Greenhalgh,DA;Quintanilla,MI;Orengo,CC;Barber,JL;Eckhardt,JN;Rothnagel,JA;Roop,DR
通讯作者:
Roop,DR
影响因子:
56.9
作者:
ADAMS, JM;CORY, S
通讯作者:
CORY, S
影响因子:
8
作者:
Burns Pa;Christopher J. Kemp;Gannon Jv;David P. Lane;R. Bremner;Allan Balmain
通讯作者:
Burns Pa;Christopher J. Kemp;Gannon Jv;David P. Lane;R. Bremner;Allan Balmain
影响因子:
11.2
作者:
T. Tennenbaum;S. Yuspa;A. Grover;V. Castronovo;M. Sobel;Yoshihiko Vainada;L. M. Luca
通讯作者:
T. Tennenbaum;S. Yuspa;A. Grover;V. Castronovo;M. Sobel;Yoshihiko Vainada;L. M. Luca