Hepatic Vasculopathy and Regenerative Responses of the Liver in Fatal Cases of COVID-19.
Hepatic Vasculopathy and Regenerative Responses of the Liver in Fatal Cases of COVID-19.
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DOI:
10.1016/j.cgh.2021.01.044
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发表时间:
2021-08
期刊:
影响因子:
--
通讯作者:
Schulte Am Esch J
中科院分区:
文献类型:
--
作者:
Kaltschmidt B;Fitzek ADE;Schaedler J;Förster C;Kaltschmidt C;Hansen T;Steinfurth F;Windmöller BA;Pilger C;Kong C;Singh K;Nierhaus A;Wichmann D;Sperhake J;Püschel K;Huser T;Krüger M;Robson SC;Wilkens L;Schulte Am Esch J
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infects the nasopharynx and lungs and causes coronavirus disease-2019 (COVID-19). It may impact the heart, brain, kidney, and liver.1 Although functional impairment of the liver has been correlated with worse clinical outcomes, little is known about the pathophysiology of hepatic injury and repair in COVID-19.2,3 Histologic evaluation has been limited to small numbers of COVID-19 cases with no control subjects2,4 and demonstrated largely heterogeneous patterns of pathology.2,3
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