In vitro antimicrobial sensitivity of enteric rods and pseudomonads from advanced adult periodontitis.
In vitro antimicrobial sensitivity of enteric rods and pseudomonads from advanced adult periodontitis.
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晚期成人牙周炎肠杆和假单胞菌的体外抗菌敏感性。
DOI:
10.1111/j.1399-302x.1990.tb00428.x
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发表时间:
1990
影响因子:
--
通讯作者:
Rams,TE
中科院分区:
文献类型:
--
作者:
Slots,J;Feik,D;Rams,TE
The prevalence andin vitroantimicrobial sensitivity of isolates of enteric rods and pseudomonads was examined in 844 adult periodontitis patients. These organisms were recovered from 13.5% of the study subjects. Ciprofloxacin exhibited the highest inhibitory activity of the 14 oral antimicrobial agents tested. Beta‐lactam antibiotics were largely ineffective, and tetracycline failed to inhibit mostPseudomonasspecies.In vitrosensitivity data suggest that a subgingival microbiota comprising mainly streptococci would result from therapy that combined ciprofloxacin and metronidazole. Since streptococci may inhibit the growth of several putative periodontal pathogens, populations of “beneficial” streptococci in the periodontal pocket might constitute a very attractive therapeutic outcome. Controlled clinical studies are needed to clarify the possible role of ciprofloxacin in the treatment of destructive periodontitis.
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期刊:
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