Normative data for ages 18-45 for ocular motor and vestibular testing using eye tracking.

Normative data for ages 18-45 for ocular motor and vestibular testing using eye tracking.
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DOI:
10.1002/lio2.632
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发表时间:
2021-10
影响因子:
1.9
通讯作者:
Kiderman A
Kiderman A
中科院分区:
医学3区
文献类型:
--
作者:
Kullmann A;Ashmore RC;Braverman A;Mazur C;Snapp H;Williams E;Szczupak M;Murphy S;Marshall K;Crawford J;Balaban CD;Hoffer M;Kiderman A

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眼动追踪技术已被用于评估前庭和神经系统疾病,包括创伤性脑损伤(TBI)后的眼运动和前庭功能。评估包括提供视觉和运动(旋转)刺激的测试,同时记录水平、垂直和扭转眼球运动。虽然其中一些测试在以前的研究中显示出诊断的希望,但由于缺乏规范数据,它们在临床实践中的应用受到限制。本研究的目的是建立规范的参考范围,用于比较患者的结果。对年龄在18 - 45岁、无神经、前庭疾病或其他头部损伤的男性和女性志愿者进行了光动力学反应、主观视觉水平和垂直以及旋转测试。测试使用旋转椅或配备视频视觉术的便携式虚拟现实护目镜进行。对290至449名参与者在不同刺激模式下的眼球运动参考值进行了分析。将性别(自我报告)或年龄分组为儿科(青少年晚期;18 - 21岁)和成人(21 - 45岁)时,分析显示对测试指标没有影响。将数据汇总,并将每个测试指标作为95%参考区间(RI),并在RI的上限和下限上设置90%置信区间(CI)。该规范数据库可作为前庭和神经系统疾病的诊断、治疗和/或康复方案的辅助工具,包括轻度TBI (mTBI)。该数据库已被FDA批准用于临床实践(K192186)。2 b
Eye tracking technology has been employed in assessing ocular motor and vestibular function following vestibular and neurologic conditions, including traumatic brain injury (TBI). Assessments include tests that provide visual and motion (rotation) stimuli while recording horizontal, vertical, and torsional eye movements. While some of these tests have shown diagnostic promise in previous studies, their use in clinical practice is limited by the lack of normative data. The goal of this study was to construct normative reference ranges to be used when comparing patients' results. Optokinetic response, subjective visual horizontal and vertical, and rotation tests were administered to male and female volunteers, ages 18‐45, who were free from neurological, vestibular disorders, or other head injuries. Tests were administered using either a rotatory chair or a portable virtual reality‐like goggle equipped with video‐oculography. Reference values for eye movements in response to different patterns of stimuli were analyzed from 290 to 449 participants. Analysis of gender (self‐reported) or age when grouped as pediatric (late adolescent; 18‐21 years of age) and adult (21‐45 years of age) revealed no effects on the test metrics. Data were pooled and presented for each test metric as the 95% reference interval (RI) with 90% confidence intervals (CI) on upper and lower limits of the RI. This normative database can serve as a tool to aid in diagnosis, treatment, and/or rehabilitation protocols for vestibular and neurological conditions, including mild TBI (mTBI). This database has been cleared by the FDA for use in clinical practice (K192186). 2b
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