STEM mode in the SEM for the analysis of cellular sections prepared by ultramicrotome sectioning

STEM mode in the SEM for the analysis of cellular sections prepared by ultramicrotome sectioning
复制标题

SEM 中的 STEM 模式用于分析超薄切片机制备的细胞切片

DOI:
10.1088/1742-6596/371/1/012021
复制
发表时间:
2012
期刊:
Conference Series
影响因子:
--
通讯作者:
Hondow N
Hondow N
中科院分区:
--
文献类型:
--
作者:
Hondow N

文献摘要

参考文献

相似文献

在纳米毒理学领域具有重要性的样品分析中,突出了配备有透射电子检测器的扫描电子显微镜的双重成像能力的使用。纳米材料的细胞摄取通常通过超薄切片机制备的薄切片的透射电子显微镜检查。通过SEM检查可以检测样品制备引起的伪影(例如,纳米材料拉出)和互补的STEM模式允许研究纳米材料和细胞之间的相互作用。在扫描电镜中使用STEM模式检查了两种在纳米毒理学中具有重要意义的纳米材料(硒化镉量子点和单壁碳纳米管)的薄切片。
The use of the dual imaging capabilities of a scanning electron microscope fitted with a transmitted electron detector is highlighted in the analysis of samples with importance in the field of nanotoxicology. Cellular uptake of nanomaterials is often examined by transmission electron microscopy of thin sections prepared by ultramicrotome sectioning. Examination by SEM allows for the detection of artefacts caused by sample preparation (eg. nanomaterial pull-out) and the complementary STEM mode permits study of the interaction between nanomaterials and cells. Thin sections of two nanomaterials of importance in nanotoxicology (cadmium selenide quantum dots and single walled carbon nanotubes) are examined using STEM mode in the SEM.
DOI: 10.1093/toxsci/kfq372
发表时间: 2011-03-01
影响因子: 3.8
作者:
Maynard, Andrew D.;Warheit, David B.;Philbert, Martin A.
通讯作者: Philbert, Martin A.
细胞电子显微镜
DOI: --
发表时间: 2007
期刊:
影响因子: --
作者:
J. McIntosh
通讯作者: J. McIntosh