A systematic review of sleep deprivation and neurobehavioral function in young adults.

A systematic review of sleep deprivation and neurobehavioral function in young adults.
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DOI:
10.1016/j.apnr.2021.151552
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发表时间:
2022-03
期刊:
Applied nursing research : ANR
影响因子:
--
通讯作者:
Hickman RL Jr
Hickman RL Jr
中科院分区:
其他
文献类型:
--
作者:
Griggs S;Harper A;Hickman RL Jr

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在18-30岁的年轻人中,研究睡眠剥夺(全部和部分)对神经行为功能的影响,并与健康的睡眠机会(7-9小时)进行比较。超过三分之一的年轻人被剥夺了睡眠,这对一系列神经行为功能产生了负面影响,包括精神警觉性(认知),情感和白天嗜睡。关于睡眠剥夺和神经行为功能的随机对照试验(RCT)的系统综述。检索多个电子数据库(科克伦对照试验中心[CENTRAL]、PubMed、PsycINFO、CINAHL和Web of Science),查找自各数据库建立至2020年12月31日以英文发表的相关RCT。选择了19项RCT(N = 766,平均年龄= 23.7 ± 3.1岁; 44.8%为女性)。7项为人间设计(5项为平行组设计,2项为多组设计),12项为人内设计(9项为交叉设计,3项使用拉丁方方法)。在纳入的研究中,完全睡眠剥夺对精神运动性警惕表现的不利影响最大,对年轻人的警惕任务的影响最大。急性睡眠剥夺会降低年轻人神经行为功能的多个维度,包括精神警觉性、情感和日间嗜睡。长期睡眠剥夺对年轻人大脑发育和相关神经行为功能的影响尚不清楚。
To examine the effect of sleep deprivation (total and partial) on neurobehavioral function compared to a healthy sleep opportunity (7–9 hours) in young adults 18–30 years. More than one-third of young adults are sleep deprived, which negatively affects a range of neurobehavioral functions, including psychomotor vigilance performance (cognitive), affect, and daytime sleepiness. A systematic review of randomized controlled trials (RCTs) on sleep deprivation and neurobehavioral function. Multiple electronic databases (Cochrane Central Registry of Controlled Trials [CENTRAL], PubMed, PsycINFO, CINAHL, and Web of Science) were searched for relevant RCTs published in English from the establishment of each database to December 31, 2020. Nineteen RCTs were selected (N = 766, mean age = 23.7 ± 3.1 years; 44.8% female). Seven were between-person (5 were parallel-group designs and 2 had multiple arms), and 12 were within-person designs (9 were cross over and 3 used a Latin square approach). Total sleep deprivation had the strongest detrimental effect on psychomotor vigilance performance, with the largest effects on vigilance tasks in young adults in the included studies. Acute sleep deprivation degrades multiple dimensions of neurobehavioral function including psychomotor vigilance performance, affect, and daytime sleepiness in young adults. The effect of chronic sleep deprivation on the developing brain and associated neurobehavioral functions in young adults remains unclear.
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