Calcium signaling in intracellular protist parasites.

Calcium signaling in intracellular protist parasites.
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DOI:
10.1016/j.mib.2021.09.002
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发表时间:
2021-12
影响因子:
5.4
通讯作者:
Moreno SN
Moreno SN
中科院分区:
生物学2区
文献类型:
--
作者:
Docampo R;Moreno SN

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钙离子(Ca~(2+))信号转导机制是真核细胞最常用的信号转导机制之一,从细胞内钙离子释放或钙离子通过质膜进入细胞内开始。在胞内原生生物中,Ca~(2+)信号启动一系列事件,促进其入侵宿主细胞,响应宿主内环境的变化,或调节其胞内细胞器的功能。在这篇综述中,我们检查了两组细胞内原生寄生虫中钙信号的最新发现,这两组原生寄生虫已经得到了更详细的研究,顶复合体寄生虫和锥虫寄生虫。
Calcium ion (Ca2+) signaling is one of the most frequently employed mechanisms of signal transduction by eukaryotic cells, and starts with either Ca2+ release from intracellular stores or Ca2+ entry through the plasma membrane. In intracellular protist parasites Ca2+ signaling initiates a sequence of events that may facilitate their invasion of host cells, respond to environmental changes within the host, or regulate the function of their intracellular organelles. In this review we examine recent findings in Ca2+ signaling in two groups of intracellular protist parasites that have been studied in more detail, the apicomplexan and the trypanosomatid parasites.
DOI: 10.1186/1475-2875-12-41
发表时间: 2013-01-30
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