Muscarinic receptor subtypes: modulation of ion channels.
Muscarinic receptor subtypes: modulation of ion channels.
复制标题
毒蕈碱受体亚型:离子通道的调节。
DOI:
10.1016/0024-3205(93)90302-j
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发表时间:
1993
期刊:
影响因子:
6.1
通讯作者:
S. Jones
中科院分区:
文献类型:
--
作者:
S. Jones
The discovery of five muscarinic receptor subtypes by molecular genetic techniques has resulted in new approaches to understanding their function. This involves the expression of the individual genes encoding each receptor subtype in isolation, such that their effects and mechanisms of action can be studied. The coupling of the receptors with G-proteins and ion channels is the subject of this review and emphasis is placed upon the assignment of genetically defined receptor subtypes with a given physiological function. Activation of inwardly rectifying potassium conductances by m2 and m4 and inhibition by m1, as well as stimulation of calcium-dependent conductances by m1, m3 and m5 are discussed.
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DOI:
--
发表时间:
1990
期刊:
The Journal of pharmacology and experimental therapeutics
影响因子:
--
作者:
Lacey,MG;Calabresi,P;North,RA
通讯作者:
North,RA
影响因子:
56.9
作者:
Wei-Jen Tang;A. Gilman
通讯作者:
Wei-Jen Tang;A. Gilman
DOI:
10.1126/science.1553544
发表时间:
1992
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Martin,GA;Yatani,A;Clark,R;Conroy,L;Polakis,P;Brown,AM;McCormick,F
通讯作者:
McCormick,F
影响因子:
3.6
作者:
Hartzell,HC;Fischmeister,R
通讯作者:
Fischmeister,R
DOI:
10.1113/jphysiol.1990.sp017989
发表时间:
1990-03
期刊:
The Journal of Physiology
影响因子:
--
作者:
N. Uchimura;R. North
通讯作者:
N. Uchimura;R. North