Costing oral cholera vaccine delivery using a generic oral cholera vaccine delivery planning and costing tool (CholTool).

Costing oral cholera vaccine delivery using a generic oral cholera vaccine delivery planning and costing tool (CholTool).
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DOI:
10.1080/21645515.2020.1747930
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发表时间:
2020-12-01
影响因子:
4.8
通讯作者:
Mogasale V
Mogasale V
中科院分区:
医学3区
文献类型:
--
作者:
Morgan W;Levin A;Hutubessy RC;Mogasale V

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在许多低收入和中等收入国家(LMIC),霍乱既是地方病又是流行病。霍乱控制策略包括改善水、环境卫生和个人卫生;提供早期有效的治疗;并部署口服霍乱疫苗(OCV)。最后一种策略相对较新,考虑引入该策略的国家不仅有兴趣了解疫苗的潜在成本,而且有兴趣了解引入成本。本文描述了使用基于 Excel 的公开工具(称为 CholTool)在中低收入国家引入 OCV 的成本计算。它包括交付成本类别的估计,不仅涵盖服务交付成本(例如疫苗采购、处理、储存和运输;疫苗接种管理、监测监督和现场支持),还包括与引入新疫苗相关的计划成本(即微观规划、沟通和培训材料开发、宣传/社会动员和人员培训),以确保从卫生支付者的角度提供全面的估计。 CholTool 引导用户通过包含输入参数单元(假设)、决策单元(变量选择)和公式(计算)的互连模块的结构化序列,以根据标准化方法生成定制的成本估算。该工具提供财务和经济成本估算,以确保这两种成本都可供考虑。三个国家介绍了 CholTool 的四个应用示例——一个在埃塞俄比亚,两个在马拉维,一个在尼泊尔。每剂经济交付成本(包括服务交付和规划成本)估计为(以 2016 年美元计):埃塞俄比亚 2.89 美元,马拉维1 3.04 美元,马拉维2 3.35 美元,尼泊尔 3.06 美元。在活动之前使用该工具进行的成本预测以及在尼泊尔使用该工具进行的回顾性成本计算表明,每剂的经济交付成本之间没有显着差异。
Cholera is both an endemic and epidemic disease in many low and middle-income countries (LMICs). Strategies for cholera control include improving water, sanitation, and hygiene; providing early and effective treatment; and deploying oral cholera vaccine (OCV). This last strategy is relatively new, and countries considering its introduction are interested in knowing the potential cost not only of the vaccine, but also the cost of introduction. This paper describes the costing of OCV introduction in LMICs using a publicly available Excel-based tool known as the CholTool. It includes estimates of delivery cost categories which cover not only the service delivery costs (e.g. vaccine procurement, handling, storage, and transport; vaccination administration, monitoring supervision, and field support), but also the programmatic costs associated with introducing a new vaccine (i.e. microplanning, communication and training materials development, sensitization/social mobilization, and personnel training) to ensure that a comprehensive estimate is provided with health payer perspective. CholTool takes the user through a structured sequence of interlinked modules containing input parameter cells (assumptions), decision cells (variable selections), and formulas (calculations) to produce customized cost estimates based on standardized methods. The tool provides both financial and economic cost estimates, to ensure that both costs are available for consideration. Four examples of applications of CholTool are presented in three countries- one in Ethiopia, two in Malawi and one in Nepal. The estimates of economic delivery cost per dose (including service delivery and programmatic costs) were (in USD 2016): $2.89 in Ethiopia, $3.04 in Malawi1, $3.35 in Malawi2 and $3.06 in Nepal. A cost projection conducted before the campaign using the tool and a retrospective costing using the tool in Nepal resulted in no significant difference between economic delivery costs per dose.
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发表时间: 2018
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