Driving Factors of Preterm Birth Risk in Adolescents.
Driving Factors of Preterm Birth Risk in Adolescents.
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DOI：
10.1055/s-0040-1715164
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发表时间：
2020-07
期刊：
影响因子：
0.9
通讯作者：
Stout MJ
中科院分区：
文献类型：
--
作者：
Perez MJ;Chang JJ;Temming LA;Carter EB;López JD;Tuuli MG;Macones GA;Stout MJ
目的 我们检查了青少年自发早产率和指示早产率（分别为 S-PTB 和 I-PTB）以及 PTB 的临床危险因素。 研究设计 这是一个基于人群的回顾性队列，使用 2012 年美国未产妇的出生数据，这些妇女在妊娠 20 至 42 周之间产下非异常单胎。产妇年龄包括<16岁、16至19.9岁和≥20岁。比较不同年龄组的总 PTB 率、S-PTB 率和 I-PTB 率。多项逻辑回归测试了 S-PTB 的临床危险因素。 结果 在 1,342,776 例妊娠中，青少年患 PTB 的风险高于成人。年轻青少年的总 PTB 发生率最高，为 10.6%，老年青少年下降至 8.3%，成人为 7.8%。 S-PTB 的比例在最年轻的青少年中最高，并在成年后逐渐下降； I-PTB 的比例在各个年龄组中保持稳定。青少年 S-PTB 的危险因素包括亚洲人种、体重指数 (BMI) 过低和妊娠期体重增加 (GWG) 不良。在所有年龄组中，怀有男性胎儿的 S-PTB 均显着增加，而妇女、婴儿和儿童 (WIC) 的参与与风险显着降低相关。 结论 青少年 PTB 风险较高是由 S-PTB 风险增加所致。低 BMI 和低 GWG 可能是潜在的可改变的风险因素。 冷凝 青少年发生自发性 PTB 的风险高于成年女性，且青少年发生自发性 PTB 的危险因素可能有所不同。
Objective We examined rates of spontaneous and indicated preterm births (S-PTB and I-PTB, respectively) and clinical risk factors for PTB in adolescents. Study Design This is a population-based, retrospective cohort using 2012 U.S. natality data of nulliparous women who delivered a nonanomalous singleton birth between 20 and 42 weeks' gestation. Maternal age included <16, 16 to 19.9, and ≥20 years. Rates of total, S-PTB, and I-PTB were compared across age groups. Multinomial logistic regression tested clinical risk factors for S-PTB. Results In 1,342,776 pregnancies, adolescents were at higher risk for PTB than adults. The rate of total PTB was highest in young adolescents at 10.6%, decreased to 8.3% in older adolescents, and 7.8% in adults. The proportion of S-PTB was highest in the youngest adolescents and decreased toward adulthood; the proportion of I-PTB remained stable across age groups. Risk factors for S-PTB in adolescents included Asian race, underweight body mass index (BMI), and poor gestational weight gain (GWG). In all age groups, carrying a male fetus showed a significant increased S-PTB, and Women, Infants, and Children's (WIC) participation was associated with a significantly decreased risk. Conclusion The higher risk for PTB in adolescents is driven by an increased risk for S-PTB. Low BMI and poor GWG may be potentially modifiable risk factors. Condensation Adolescents have a higher risk for spontaneous PTB than adult women, and risk factors for spontaneous PTB may differ in adolescents.
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