Beetroot juice supplementation reduces whole body oxygen consumption but does not improve indices of mitochondrial efficiency in human skeletal muscle
Beetroot juice supplementation reduces whole body oxygen consumption but does not improve indices of mitochondrial efficiency in human skeletal muscle
复制标题
补充甜菜根汁可降低全身耗氧量，但不会提高人体骨骼肌线粒体效率指数
DOI：
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
Graham P. Holloway
中科院分区：
文献类型：
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作者：
Jamie Whitfield;Alison Ludzki;G. Heigenhauser;J. Senden;L. Verdijk;L. V. Loon;L. Spriet;Graham P. Holloway
口服甜菜根汁中的硝酸盐（NO3−）已被证明可以降低次极量运动的耗氧量;然而，其作用机制尚未得到解决。我们用甜菜根汁补充娱乐活跃的男性，以确定这是否改变了线粒体生物能量学。尽管减少亚极量运动耗氧量，线粒体偶联和呼吸效率的措施没有改变肌肉。与此相反，线粒体过氧化氢（H2 O2）的排放率增加的情况下，脂质或蛋白质氧化损伤的标志物。这些结果表明，线粒体氧化代谢的改善不是甜菜根汁介导的全身耗氧量改善的原因。
Oral consumption of nitrate (NO3−) in beetroot juice has been shown to decrease the oxygen cost of submaximal exercise; however, the mechanism of action remains unresolved. We supplemented recreationally active males with beetroot juice to determine if this altered mitochondrial bioenergetics. Despite reduced submaximal exercise oxygen consumption, measures of mitochondrial coupling and respiratory efficiency were not altered in muscle. In contrast, rates of mitochondrial hydrogen peroxide (H2O2) emission were increased in the absence of markers of lipid or protein oxidative damage. These results suggest that improvements in mitochondrial oxidative metabolism are not the cause of beetroot juice‐mediated improvements in whole body oxygen consumption.
影响因子：
15.9
作者：
Anderson, Ethan J.;Lustig, Mary E.;Neufer, P. Darrell
通讯作者：
Neufer, P. Darrell
影响因子：
33.6
作者：
Powers SK;Jackson MJ
通讯作者：
Jackson MJ