Evaluation of Ultrasound Biomicroscopy Combined with Color Doppler Flow Imaging in the Diagnosis of Primary Lacrimal Canaliculitis
Evaluation of Ultrasound Biomicroscopy Combined with Color Doppler Flow Imaging in the Diagnosis of Primary Lacrimal Canaliculitis
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超声生物显微镜联合彩色多普勒超声诊断原发性泪小管炎的评价
DOI：
10.1080/09273948.2020.1738499
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发表时间：
2020-04
期刊：
影响因子：
--
通讯作者：
Yuan Y
中科院分区：
文献类型：
--
作者：
Chen Q;Ma R;Yi X;Gan L;Cheng Y;Zhang R;Qian J;Yuan Y
摘要目的：探讨超声生物显微镜(UBM)和彩色多普勒血流成像(CDFI)对原发性泪小管炎的诊断价值。方法：前瞻性招募有相关小管炎症状的受试者。UBM和CDFI用于推定诊断。进行微生物学和组织病理学检查以明确诊断。结果：共纳入37例，其中小管炎25例，非小管炎12例。13例小管炎患者中检出病原菌13例，主要病原菌为放线菌(4例)和链球菌(4例)。UBM和CDFI诊断24例小管炎(敏感性=96%)和11例非小管炎(特异性=92%)。管腔壁厚0.25 mm(P=0.019)和管内结石(P=0.010)是小管炎的预测因素。其他典型表现为管腔增大(2.16±0.25 mm)和热轮签约CDFI(84%)。这些影像表现与组织病理学改变相一致。结论：超声检查对小管炎的诊断有重要价值。(临床试验注册号：ChiCTR1900025411)
ABSTRACT Purpose: To explore the performance of ultrasound biomicroscopy (UBM) and color Doppler flow imaging (CDFI) in the diagnosis of primary lacrimal canaliculitis. Methods: Subjects with relevant symptoms of canaliculitis were prospectively recruited. UBM and CDFI were performed for presumptive diagnosis. Microbiology and histopathology were performed for definitive diagnosis. Results: A total of 37 cases were recruited, including 25 cases of canaliculitis and 12 cases of non-canaliculitis. Pathogens were isolated in 13 canaliculitis cases, and the leading pathogens were Actinomyces (4 cases) and Streptococcus (4 cases). UBM and CDFI identified 24 canaliculitis cases (sensitivity = 96%) and 11 non-canaliculitis cases (specificity = 92%). The predictive factors for canaliculitis were lumen wall thickness >0.25 mm (P = .019) and intracanalicular concretions (P = .010). Other typical features were enlarged lumen (2.16 ± 0.25 mm) and hot-wheel sign-on CDFI (84%). These image findings were congruent with histopathologic changes. Conclusion: Ultrasonography is a valuable tool to assist the diagnosis of canaliculitis. (Clinical trial registration number: ChiCTR1900025411)
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