Continuous Glucose Monitoring in the Intensive Care Unit Following Total Pancreatectomy with Islet Autotransplantation in Children: Establishing Accuracy of the Dexcom G6 Model.
Continuous Glucose Monitoring in the Intensive Care Unit Following Total Pancreatectomy with Islet Autotransplantation in Children: Establishing Accuracy of the Dexcom G6 Model.
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儿童全胰腺切除联合胰岛自体移植后重症监护室的持续葡萄糖监测：建立Dexcom G6模型的准确性。
DOI：
10.3390/jcm10091893
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发表时间：
2021-04-27
影响因子：
3.9
通讯作者：
Elder DA
中科院分区：
文献类型：
--
作者：
Segev N;Hornung LN;Tellez SE;Courter JD;Lawson SA;Nathan JD;Abu-El-Haija M;Elder DA
高血压对接受全胰腺切除联合胰岛自体移植（TPIAT）的患者术后胰岛细胞存活不利。这使得连续血糖监测（CGM）成为一种有用的管理工具。我们评价了TPIAT后Dexcom G6 CGM在儿科重症监护室患者中的准确性。与配对血清葡萄糖值相比，25例接受TPIAT的患者具有Dexcom G6葡萄糖值。在TPIAT后的前7天内，在5分钟内获得所有配对的葡萄糖样本。使用平均绝对差（MAD）、平均绝对相对差（MARD）、%20/20、%15/15准确度和Clarke误差网格分析评价数据。排除包括CGM“预热”期间的分析和羟基脲给药（已知药物干扰）。在术后第2-7天共审查了183份时间匹配的样本。MAD为14.7 mg/dL，MARD为13.4%，第2、3、4、5、6和7天的数值分别为15.2%、14.0%、12.1%、11.4%、13.2%和14.1%。Dexcom G6的%20/20准确度为78%，%15/15准确度为64%。Clarke误差网格分析显示，77%的时间匹配值在临床上准确，100%在临床上可接受。Dexcom G6 CGM可能是产生临床可接受值的准确工具，可在TPIAT后即刻做出可靠的临床决策。
Hyperglycemia is detrimental to postoperative islet cell survival in patients undergoing total pancreatectomy with islet autotransplantation (TPIAT). This makes continuous glucose monitoring (CGM) a useful management tool. We evaluated the accuracy of the Dexcom G6 CGM in pediatric intensive care unit patients following TPIAT. Twenty-five patients who underwent TPIAT had Dexcom G6 glucose values compared to paired serum glucose values. All paired glucose samples were obtained within 5 minutes of each other during the first seven days post TPIAT. Data were evaluated using mean absolute difference (MAD), mean absolute relative difference (MARD), %20/20, %15/15 accuracy, and Clarke Error Grid analysis. Exclusions included analysis during the CGM “warm-up” period and hydroxyurea administration (known drug interference). A total of 183 time-matched samples were reviewed during postoperative days 2–7. MAD was 14.7 mg/dL and MARD was 13.4%, with values of 15.2%, 14.0%, 12.1%, 11.4%, 13.2% and 14.1% at days 2, 3, 4, 5, 6 and 7, respectively. Dexcom G6 had a %20/20 accuracy of 78%, and a %15/15 accuracy of 64%. Clarke Error Grid analysis showed that 77% of time-matched values were clinically accurate, and 100% were clinically acceptable. The Dexcom G6 CGM may be an accurate tool producing clinically acceptable values to make reliable clinical decisions in the immediate post-TPIAT period.
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DOI：
10.1097/mpg.0000000000001314
发表时间：
2017-03
影响因子：
2.9
作者：
Bellin MD;Forlenza GP;Majumder K;Berger M;Freeman ML;Beilman GJ;Dunn TB;Pruett TL;Murati M;Wilhelm JJ;Cook M;Sutherland DE;Schwarzenberg SJ;Chinnakotla S
通讯作者：
Chinnakotla S
影响因子：
1.3
作者：
Elder, Deborah A.;Jiminez-Vega, Jose M.;Nathan, Jaimie D.
通讯作者：
Nathan, Jaimie D.
影响因子：
5.4
作者：
Tellez, Siobhan E.;Hornung, Lindsey N.;Elder, Deborah A.
通讯作者：
Elder, Deborah A.
影响因子：
26.1
作者：
Kumar S;Ooi CY;Werlin S;Abu-El-Haija M;Barth B;Bellin MD;Durie PR;Fishman DS;Freedman SD;Gariepy C;Giefer MJ;Gonska T;Heyman MB;Himes R;Husain SZ;Lin TK;Lowe ME;Morinville V;Palermo JJ;Pohl JF;Schwarzenberg SJ;Troendle D;Wilschanski M;Zimmerman MB;Uc A
通讯作者：
Uc A
影响因子：
5.1
作者：
Schwarzenberg, Sarah Jane;Bellin, Melena;Husain, Sohail Z.;Ahuja, Monika;Barth, Bradley;Davis, Heather;Durie, Peter R.;Fishman, Douglas S.;Freedman, Steven D.;Gariepy, Cheryl E.;Giefer, Matthew J.;Gonska, Tanja;Heyman, Melvin B.;Himes, Ryan;Kumar, Soma;Morinville, Veronique D.;Lowe, Mark E.;Nuehring, Neil E.;Ooi, Chee Y.;Pohl, John F.;Troendle, David;Werlin, Steven L.;Wilschanski, Michael;Yen, Elizabeth;Uc, Aliye
通讯作者：
Uc, Aliye