Pinopsin expressed in the retinal photoreceptors of a diurnal gecko
Pinopsin expressed in the retinal photoreceptors of a diurnal gecko
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Pinopsin 在昼间壁虎的视网膜感光器中表达
DOI：
10.1016/s0014-5793(01)02395-x
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发表时间：
2001
期刊：
影响因子：
3.5
通讯作者：
F. Tokunaga
中科院分区：
文献类型：
--
作者：
Y. Taniguchi;O. Hisatomi;Masao Yoshida;F. Tokunaga
从夜行壁虎（Phelsuma madagascar longinsule）中分离到编码视蛋白dg3和dg4的视网膜cdna。dg3 mRNA位于约20%的C型双锥细胞的薄成员中，并可能编码紫外线敏感色素的视蛋白。令人惊讶的是，dg4与鸡松果体特异性感光分子pinopsin非常相似。抗dg4抗血清识别视网膜中少量的感光细胞外段和大量的松果体细胞。我们的研究结果表明，长叶斑蝶在其视网膜中表达pinopsin，该分子通常在松果体器官中起感光分子的作用。
Retinal cDNAs encoding the putative opsins, dg3 and dg4, were isolated from a diurnal gecko, Phelsuma madagascariensis longinsulae. dg3 mRNA is localized in about 20% of the thin members of type C double cones, and likely encodes an opsin of the ultraviolet-sensitive pigment. Surprisingly, dg4 is very similar to chicken pinopsin, a pineal-specific photoreceptive molecule. An anti-dg4 antiserum recognized a small population of photoreceptor outer segments in the retina and a large number of pinealocytes. Our results suggest that P. m. longinsulae expresses pinopsin in its retina, which usually plays a role as a photoreceptive molecule in the pineal organ.
DOI：
10.1073/pnas.89.15.6841
发表时间：
1992-08-01
影响因子：
11.1
作者：
KOJIMA, D;OKANO, T;EBREY, TG
通讯作者：
EBREY, TG