Dynamic Remodeling of Human Arteriovenous Fistula Wall Obtained From Magnetic Resonance Imaging During the First 6 Months After Creation.
Dynamic Remodeling of Human Arteriovenous Fistula Wall Obtained From Magnetic Resonance Imaging During the First 6 Months After Creation.
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DOI：
10.1016/j.ekir.2022.05.016
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发表时间：
2022-08
影响因子：
6
通讯作者：
Shiu, Yan-Ting
中科院分区：
文献类型：
--
作者：
Li, Yingnan;He, Yong;Falzon, Isabelle;Fairbourn, Brayden;Tingey, Spencer;Imrey, Peter B.;Radeva, Milena K.;Beck, Gerald J.;Gassman, Jennifer J.;Roy-Chaudhury, Prabir;Berceli, Scott A.;Cheung, Alfred K.;Shiu, Yan-Ting
关键词：
The nonmaturation rate of arteriovenous fistulas (AVFs) is high. 1 The direct connection of the AVF vein and artery creates a short path that bypasses the distal high-resistance vasculature, resulting in an immediate increase in the flow rate and venous pressure. With the endothelium-dependent flow dilation and increased distention by elevated intraluminal pressure for the vein, the AVF lumen diameter increases immediately, resulting in a thinner wall and increased hoop stress within the wall immediately after AVF creation. Thereafter, in response to increased intramural stress, veins gradually thicken. Nevertheless, quantitative data describing how much and how fast human AVF venous wall thickness increases over time are very limited in the literature. Whether AVF wall thickness is correlated with lumen area is also not known.Currently, measurements of human AVF vein wall thickness have been largely limited to histologic analysis of stenotic veins obtained during interventions, 2 rarely noninvasively in vivo. To the best of our knowledge, only 1 study measured AVF vein intima-media thickness over time by ultrasound and only in 6 patients from 1 center. 3 In addition, human AVF arterial walls and their changes over time have not been investigated. In this study, we used noncontrast, high-resolution black-blood magnetic resonance imaging (MRI) to evaluate the wall thickness and area of the AVF vein and proximal artery, along with the vein lumen area, within 6 months after AVF creation. We hypothesize that during AVF development, the AVF wall thickens in response to lumen enlargement. The detailed methods are given in Supplementary Methods.
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影响因子：
1.9
作者：
Lee, Timmy;Somarathna, Maheshika;Roy-Chaudhury, Prabir
通讯作者：
Roy-Chaudhury, Prabir
DOI：
10.1053/j.ajkd.2017.11.020
发表时间：
2018-06
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
--
作者：
Woodside KJ;Bell S;Mukhopadhyay P;Repeck KJ;Robinson IT;Eckard AR;Dasmunshi S;Plattner BW;Pearson J;Schaubel DE;Pisoni RL;Saran R
通讯作者：
Saran R
DOI：
10.2215/cjn.13431217
发表时间：
2018-09-07
影响因子：
9.8
作者：
Allon, Michael;Litovsky, Silvio H.;Shiu, Yan-Ting
通讯作者：
Shiu, Yan-Ting
影响因子：
6.1
作者：
Corpataux, JM;Haesler, E;Hayoz, D
通讯作者：
Hayoz, D
影响因子：
6.1
作者：
Lee, Timmy;Chauhan, Vibha;Roy-Chaudhury, Prabir
通讯作者：
Roy-Chaudhury, Prabir