In vivo proton magnetic resonance spectroscopy of intraventricular tumours of the brain
In vivo proton magnetic resonance spectroscopy of intraventricular tumours of the brain
复制标题
脑室内肿瘤的体内质子磁共振波谱
作者：
C. Majós;C. Aguilera;M. Cos;À. Camins;A. Candiota;T. Delgado;À. Samitier;S. Castañer;J. J. Sánchez;D. Mato;J. Acebes;C. Arús
本研究的目的是评估质子磁共振光谱在脑室内肿瘤诊断中的作用。从我们的数据库中获得了涉及16种不同肿瘤类型的52个脑室内肿瘤。所有病例均在1.5 t下30和136 ms的TE下进行了单体素质子磁共振光谱分析，使用Mann-Whitney U检验来搜索每种肿瘤类型最具区别性的数据点。脑膜瘤高Glx和Ala（分别p < 0.001和p < 0.01）、转移灶高流动脂（p < 0.001）、PNET高Cho （p < 0.001）、室管膜瘤高mI + Gly （p < 0.001）、胶质囊肿无正常脑实质形态时高NAC （p < 0.01）、中枢神经细胞瘤高mI/Gly和Ala。质子磁共振光谱提供了额外的代谢信息，可用于脑室内肿瘤的诊断。
The aim of this study was to assess the usefulness of proton MR spectroscopy in the diagnosis of intraventricular tumours. Fifty-two intraventricular tumours pertaining to 16 different tumour types were derived from our database. All cases had single-voxel proton MR spectroscopy performed at TE at both 30 and 136 ms at 1.5 T. The Mann-Whitney U test was used to search for the most discriminative datapoints each tumour type. Characteristic trends were found for some groups: high Glx and Ala in meningiomas (p < 0.001 and p < 0.01, respectively), high mobile lipids in metastasis (p < 0.001), high Cho in PNET (p < 0.001), high mI + Gly in ependymoma (p < 0.001), high NAC (p < 0.01) in the absence of the normal brain parenchyma pattern in colloid cysts, and high mI/Gly and Ala in central neurocytoma. Proton MR spectroscopy provides additional metabolic information that could be useful in the diagnosis of intraventricular brain tumors.
影响因子：
19.7
作者：
Kovanlikaya, A;Panigrahy, A;Blüml, S
通讯作者：
Blüml, S
通过先进的磁共振波谱鉴别脉络丛肿瘤。
影响因子：
4.1
作者：
Krieger,MarkD;Panigrahy,Ashok;McComb,JGordon;Nelson,MarvinD;Liu,Xiaodong;Gonzalez-Gomez,Ignacio;Gilles,Floyd;Bluml,Stefan
通讯作者：
Bluml,Stefan