Non-thermal Cellular Effects of Low-power Microwave Radiation on the Lens and Lens Epithelial Cells

Non-thermal Cellular Effects of Low-power Microwave Radiation on the Lens and Lens Epithelial Cells
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低功率微波辐射对晶状体和晶状体上皮细胞的非热细胞效应

DOI:
10.1177/147323001003800301
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发表时间:
2010-06
影响因子:
1.6
通讯作者:
Yao, K.
Yao, K.
中科院分区:
医学4区
文献类型:
--
作者:
Yu, Y.;Yao, K.

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由于现代射频设备的使用越来越多,许多国家的公众对微波辐射可能对健康产生的影响表示关切。众所周知,高功率微波辐射可通过其热效应诱发白内障。目前还不清楚低功率微波辐射,特别是低于目前接触限值的辐射是否会导致白内障。本文就低功率微波辐射对透镜和透镜上皮细胞生物学效应的研究进展作一综述。据报道,暴露影响透镜透明度,改变细胞增殖和凋亡,抑制间隙连接细胞间通讯,并诱导LEC的遗传不稳定性和应激反应。这些结果提出了一个问题:周围微波环境是否会在透镜中引起非热效应,以及此类效应是否会对健康产生潜在影响。暴露于低功率微波辐射对透镜的影响需要进一步的体内研究。
Because of the increased use of modern radiofrequency devices, public concern about the possible health effects of exposure to microwave radiation has arisen in many countries. It is well established that high-power microwave radiation can induce cataracts via its thermal effects. It remains unclear whether low-power microwave radiation, especially at levels below the current exposure limits, is cataractogenic. This review summarizes studies on the biological effects of low-power microwave radiation on lens and lens epithelial cells (LECs). It has been reported that exposure affects lens transparency, alters cell proliferation and apoptosis, inhibits gap junctional intercellular communication, and induces genetic instability and stress responses in LECs. These results raise the question of whether the ambient microwave environment can induce non-thermal effects in the lens and whether such effects have potential health consequences. Further in vivo studies on the effects on the lens of exposure to low-power microwave radiation are needed.
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