Patient satisfaction with testosterone replacement therapies: the reasons behind the choices.
Patient satisfaction with testosterone replacement therapies: the reasons behind the choices.
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患者对睾酮替代疗法的满意度：选择背后的原因。
DOI：
10.1111/jsm.12369
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Lipshultz,LarryI
中科院分区：
文献类型：
--
作者：
Kovac,JasonR;Rajanahally,Saneal;Smith,RyanP;Coward,RobertM;Lamb,DoloresJ;Lipshultz,LarryI
睾酮替代疗法（TRT）治疗男性性腺功能减退症正在迅速普及和接受。选项包括凝胶，注射，和植入式皮下pellet.AimsThe本研究的目的是确定患者的满意度和原因，在性腺功能减退的男性TRT.MethodsAn匿名的，前瞻性的调查，患者的偏好率TRT在学术泌尿科诊所的男性。该调查分为多个领域，包括病人的满意度和治疗motivation.Main Outcome MeasuresPatient满意度通过匿名调查results.ResultsPatient满意度的反应，平均患者年龄为49 ± 0.7岁（n = 382）。53%的人选择注射睾酮，31%的人选择凝胶方案，17%的人选择颗粒方案。总体而言，70%的患者对其TRT感到满意，14%的患者报告不满意。凝胶（68%）、注射剂（73%）和植入式颗粒（70%）的满意率相似。医生建议是患者首选凝胶TRT的唯一重要原因（66% vs. 37%注射剂使用者vs. 31%颗粒剂使用者）。由于成本较低，注射型TRT受到青睐（35% vs. 21%凝胶用户vs. 19%颗粒用户）。微丸因易于使用（64% vs. 44%注射用户vs. 43%凝胶用户）和方便性（58% vs. 26%注射用户vs. 19%凝胶用户）而受到青睐。在最初的12个月内，颗粒的满意度有所提高。浓度和情绪的改善发生在满意的patients.ConclusionsPatients满意TRT的百分比较高。较低的成本对注射患者很重要。方便和易用性是选择颗粒治疗的核心。接受TRT治疗的男性应该被问及情绪和注意力，因为这些因素在满意的患者中表现出最大的改善。
IntroductionTestosterone replacement therapy (TRT) for male hypogonadism is rapidly gaining popularity and acceptance. Options include gels, injections, and implantable subcutaneous pellets.AimsThe aim of this study was to determine rates of patient satisfaction and reasons for patient preferences in hypogonadal men on TRT.MethodsAn anonymous, prospective survey was distributed to men presenting for TRT at an academic urology clinic. The survey was organized into multiple domains including patient satisfaction and treatment motivation.Main Outcome MeasuresPatient satisfaction responses obtained via anonymous survey.ResultsAverage patient age was 49 ± 0.7 years (n = 382). Injectable testosterone was chosen by 53%, gel‐based regimens by 31%, and pellets by 17%. Overall, 70% of patients were satisfied with their TRT and 14% reported dissatisfaction. Satisfaction rates were similar between gels (68%), injections (73%), and implantable pellets (70%). Doctor recommendation was the sole significant reason for patients preferring gel‐based TRT (66% vs. 37% injection users vs. 31% pellet users). Injectable TRT was favored because of lower cost (35% vs. 21% gel users vs. 19% pellet users). Pellets were favored for ease of use (64% vs. 44% injection users vs. 43% gel users) and convenience (58% vs. 26% injection users vs. 19% gel users). Pellets had increased rates of satisfaction within the first 12 months. Improvements in concentration and mood occurred at higher percentages in satisfied patients.ConclusionsPatients are satisfied with TRT. Lower costs are important to patients on injections. Convenience and ease of use are central in choosing pellet therapy. Men on TRT should be questioned about mood and concentration because these factors exhibited the greatest improvements in satisfied patients.
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