Menstrual cycle phase does not influence gender differences in experimental pain sensitivity.
Menstrual cycle phase does not influence gender differences in experimental pain sensitivity.
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DOI：
10.1016/j.ejpain.2009.01.002
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发表时间：
2010-01
期刊：
影响因子：
--
通讯作者：
Girdler SS
中科院分区：
文献类型：
--
作者：
Klatzkin RR;Mechlin B;Girdler SS
在48名男性和49名女性中研究了月经周期阶段对女性实验性疼痛敏感性的影响以及对疼痛敏感性的性别差异，以响应冷加压、热和缺血性疼痛。每个女性在月经周期的三个时间点随机进行测试，即早期卵泡期、晚期卵泡期和黄体期，而男性也进行了三次测试，控制测试时间之间的天数。通过血清激素水平确认周期阶段。正如预期的那样，女性对冷痛（p <0.01）、热痛（p <0.0001）和缺血性疼痛（p <0.01）的敏感性明显高于男性。然而，在每项任务中的疼痛感知并不受女性月经周期的影响，月经周期也不影响疼痛敏感性的性别差异的大小。这些结果表明，虽然女性比男性对各种伤害性刺激更敏感，但月经周期阶段似乎并没有缓和健康男性和女性的这些差异。
Influence of menstrual cycle phase on experimental pain sensitivity in women and on gender differences in pain sensitivity was examined in 48 men and 49 women in response to cold pressor, heat, and ischemic pain. Each woman was tested at three points in their menstrual cycle in randomized order, the early follicular, late follicular, and luteal phases, while men were also tested three times, controlling for number of days between test sessions. Cycle phase was confirmed via serum hormone levels. As expected, women were significantly more sensitive to cold pain (p < .01), to heat pain (p < .0001), and to ischemic pain (p < .01) than men. However, pain perception during each task was not influenced by the menstrual cycle in women, nor did the menstrual cycle influence the magnitude of the gender differences in pain sensitivity. These results indicate that although women are more sensitive to a variety of noxious stimuli than men, menstrual cycle phase does not appear to moderate those differences in healthy men and women.
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影响因子：
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