Life in an arsenic-containing gold mine: genome and physiology of the autotrophic arsenite-oxidizing bacterium rhizobium sp. NT-26.
Life in an arsenic-containing gold mine: genome and physiology of the autotrophic arsenite-oxidizing bacterium rhizobium sp. NT-26.
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DOI：
10.1093/gbe/evt061
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发表时间：
2013
影响因子：
3.3
通讯作者：
Bertin PN
中科院分区：
文献类型：
--
作者：
Andres J;Arsène-Ploetze F;Barbe V;Brochier-Armanet C;Cleiss-Arnold J;Coppée JY;Dillies MA;Geist L;Joublin A;Koechler S;Lassalle F;Marchal M;Médigue C;Muller D;Nesme X;Plewniak F;Proux C;Ramírez-Bahena MH;Schenowitz C;Sismeiro O;Vallenet D;Santini JM;Bertin PN
砷在环境中广泛存在，其存在是自然或人为活动的结果。微生物已经开发出不同的机制来处理有毒化合物，如砷，这是抵抗或代谢化合物。在这里，我们提出了第一个参考集的基因组，转录组和蛋白质组数据的α变形杆菌分离含砷金矿：根瘤菌属NT-26。虽然与植物相关的细菌在遗传学上相关，但这种生物已经失去了与豆类共生所需的主要殖民能力。相比之下，根瘤菌NT-26的基因组包含一个含有各种基因的大质粒，使其能够代谢亚砷酸盐。值得注意的是，虽然亚砷酸盐氧化和鞭毛运动/生物膜形成所需的基因分别由巨质粒和染色体携带，但观察到这两种机制的协调调节。总的来说，这些过程说明了环境压力对细菌基因组进化的影响，通过获得新功能来改善细菌菌株的适应性。
Arsenic is widespread in the environment and its presence is a result of natural or anthropogenic activities. Microbes have developed different mechanisms to deal with toxic compounds such as arsenic and this is to resist or metabolize the compound. Here, we present the first reference set of genomic, transcriptomic and proteomic data of an Alphaproteobacterium isolated from an arsenic-containing goldmine: Rhizobium sp. NT-26. Although phylogenetically related to the plant-associated bacteria, this organism has lost the major colonizing capabilities needed for symbiosis with legumes. In contrast, the genome of Rhizobium sp. NT-26 comprises a megaplasmid containing the various genes, which enable it to metabolize arsenite. Remarkably, although the genes required for arsenite oxidation and flagellar motility/biofilm formation are carried by the megaplasmid and the chromosome, respectively, a coordinate regulation of these two mechanisms was observed. Taken together, these processes illustrate the impact environmental pressure can have on the evolution of bacterial genomes, improving the fitness of bacterial strains by the acquisition of novel functions.
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影响因子：
10.7
作者：
Castresana, J
通讯作者：
Castresana, J
影响因子：
4.4
作者：
Aury JM;Cruaud C;Barbe V;Rogier O;Mangenot S;Samson G;Poulain J;Anthouard V;Scarpelli C;Artiguenave F;Wincker P
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Wincker P
影响因子：
2.8
作者：
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通讯作者：
Gadd, Geoffrey Michael
影响因子：
3.2
作者：
Eraso, Jesus M.;Roh, Jung Hyeob;Kaplan, Samuel
通讯作者：
Kaplan, Samuel
影响因子：
12.3
作者：
Daubin V;Lerat E;Perrière G
通讯作者：
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