PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes.
PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes.
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DOI:
10.1186/gb-2010-11-1-r6
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发表时间:
2010-01-20
期刊:
影响因子:
12.3
通讯作者:
Theis FJ
中科院分区:
文献类型:
--
作者:
Ruepp A;Kowarsch A;Schmidl D;Buggenthin F;Brauner B;Dunger I;Fobo G;Frishman G;Montrone C;Theis FJ
PhenomiR is a comprehensive database of 542 studies reporting deregulation of miRNAs allowing large-scale statistical analysis of miRNA expression changes. In recent years, microRNAs have been shown to play important roles in physiological as well as malignant processes. The PhenomiR database http://mips.helmholtz-muenchen.de/phenomir provides data from 542 studies that investigate deregulation of microRNA expression in diseases and biological processes as a systematic, manually curated resource. Using the PhenomiR dataset, we could demonstrate that, depending on disease type, independent information from cell culture studies contrasts with conclusions drawn from patient studies.
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