Refining immunotherapeutic approaches to high-risk neuroblastoma based on tumor genomic profiles.
Refining immunotherapeutic approaches to high-risk neuroblastoma based on tumor genomic profiles.
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基于肿瘤基因组特征，针对高危神经细胞瘤的免疫治疗方法。
DOI：
10.1002/1878-0261.12880
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发表时间：
2021-03
影响因子：
6.6
通讯作者：
Maris JM
中科院分区：
文献类型：
--
作者：
Grossmann LD;Maris JM
In this issue, Coronado et al. attempt to improve our understanding of the factors affecting the response to immunotherapy in a large subset of high‐risk neuroblastoma with hemizygous deletion of chromosome 11q. By using several computational approaches, the authors study potential transcriptional and post‐transcriptional pathways that may affect the response to immunotherapy and further be leveraged therapeutically in a biomarker‐directed fashion. Coronado et al. attempt to improve our understanding of the factors affecting the response to immunotherapy in a large subset of high‐risk neuroblastoma with hemizygous deletion of chromosome 11q. By using several computational approaches, the authors study potential transcriptional and post‐transcriptional pathways that may affect the response to immunotherapy and further be leveraged therapeutically in a biomarker‐directed fashion.
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DOI：
10.1126/science.aat6768
发表时间：
2018-12-07
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Ackermann S;Cartolano M;Hero B;Welte A;Kahlert Y;Roderwieser A;Bartenhagen C;Walter E;Gecht J;Kerschke L;Volland R;Menon R;Heuckmann JM;Gartlgruber M;Hartlieb S;Henrich KO;Okonechnikov K;Altmüller J;Nürnberg P;Lefever S;de Wilde B;Sand F;Ikram F;Rosswog C;Fischer J;Theissen J;Hertwig F;Singhi AD;Simon T;Vogel W;Perner S;Krug B;Schmidt M;Rahmann S;Achter V;Lang U;Vokuhl C;Ortmann M;Büttner R;Eggert A;Speleman F;O'Sullivan RJ;Thomas RK;Berthold F;Vandesompele J;Schramm A;Westermann F;Schulte JH;Peifer M;Fischer M
通讯作者：
Fischer M
DOI：
10.1056/nejmoa1407222
发表时间：
2014-10-16
期刊：
The New England journal of medicine
影响因子：
--
作者：
Maude SL;Frey N;Shaw PA;Aplenc R;Barrett DM;Bunin NJ;Chew A;Gonzalez VE;Zheng Z;Lacey SF;Mahnke YD;Melenhorst JJ;Rheingold SR;Shen A;Teachey DT;Levine BL;June CH;Porter DL;Grupp SA
通讯作者：
Grupp SA
影响因子：
51.1
作者：
Ladenstein, Ruth;Poetschger, Ulrike;Lode, Holger N.
通讯作者：
Lode, Holger N.
影响因子：
64.5
作者：
BERNARDS, R;DESSAIN, SK;WEINBERG, RA
通讯作者：
WEINBERG, RA
影响因子：
51.1
作者：
Geoerger, Birgit;Zwaan, C. Michel;Trippett, Tanya
通讯作者：
Trippett, Tanya