A qualitative analysis of acute skin toxicity among breast cancer radiotherapy patients.

A qualitative analysis of acute skin toxicity among breast cancer radiotherapy patients.
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DOI:
10.1002/pon.1734
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发表时间:
2011-03
期刊:
影响因子:
3.6
通讯作者:
Montgomery, Guy H.
Montgomery, Guy H.
中科院分区:
医学2区
文献类型:
--
作者:
Schnur, Julie B.;Ouellette, Suzanne C.;DiLorenzo, Terry A.;Green, Sheryl;Montgomery, Guy H.

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乳腺癌放疗最常见的急性副作用之一是治疗引起的皮肤变化,称为皮肤毒性。然而,迄今为止还没有研究明确关注乳腺癌放疗患者的皮肤毒性相关生活质量。因此,我们的目的是使用定性方法来更好地了解皮肤毒性对生活质量的影响。半结构化的采访进行了20名妇女(0-III期乳腺癌),在他们的最后一周的外照射放疗。每次访谈都逐字记录,并进行专题分析。三个主题被确定的基础上的采访回答:第一,皮肤变化影响生活质量的多个方面。它们导致身体不适,身体形象障碍,情绪困扰,并损害日常功能和对放射治疗的满意度。第二,个体差异影响妇女的经历。一般来说,非洲裔美国妇女、年轻妇女、目前没有恋爱关系的妇女、在夏季接受治疗的妇女以及对自己的外表投入更多的妇女更容易受到皮肤毒性的困扰。第三,妇女使用各种症状管理策略,包括自我药物治疗,补充/替代医学方法和心理策略。结果的含义是:1)皮肤毒性影响生活质量的许多方面,评估方法和心理社会干预措施应解决这一问题; 2)个体差异可能影响皮肤毒性的体验,应在治疗和教育方法中加以考虑; 3)应利用参与者自己的创造力和解决问题的能力来改善治疗体验。
One of the most common acute side effects of breast cancer radiotherapy is treatment induced skin changes, referred to as skin toxicity. Yet no research to date has focused expressly on skin toxicity-related quality of life in breast cancer radiotherapy patients. Therefore, our aim was to use qualitative approaches to better understand the impact of skin toxicity on quality of life. Semi-structured interviews were conducted with 20 women (Stage 0-III breast cancer), during their last week of external beam radiotherapy. Each interview was transcribed verbatim, and thematic analysis was performed. Three themes were identified based on the interview responses: First, skin changes affect multiple dimensions of quality of life. They cause physical discomfort, body image disturbance, emotional distress, and impair both day-to-day functioning and satisfaction with radiation treatment. Second, individual differences affect women’s experiences. Generally African-American women, younger women, women who are not currently in a relationship, women who are being treated during the summer, and women who are more invested in their appearance are more distressed by skin toxicity. Third, women use a variety of symptom management strategies including self-medication, complementary/alternative medicine approaches, and psychological strategies. Implications of results are: 1) Skin toxicity affects numerous dimensions of quality of life, and assessment approaches and psychosocial interventions should address this; 2) individual differences may affect the experience of skin toxicity, and should be considered in treatment and education approaches; and 3) participants’ own creativity and problem-solving should be used to improve the treatment experience.
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