Magnetic [corrected] resonance imaging [corrected] features of the disruption-prone and the disrupted carotid plaque.
Magnetic [corrected] resonance imaging [corrected] features of the disruption-prone and the disrupted carotid plaque.
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DOI：
10.1016/j.jcmg.2009.03.013
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发表时间：
2009-07
影响因子：
14
通讯作者：
Hatsukami, Thomas S.
中科院分区：
文献类型：
--
作者：
Chu, Baocheng;Ferguson, Marina S.;Chen, Huijun;Hippe, Daniel S.;Kerwin, William S.;Canton, Gador;Yuan, Chun;Hatsukami, Thomas S.
中风是导致长期残疾的主要原因，也是美国和西方国家第三大常见死因。百分之二十的中风被认为是由颈动脉引起的。组织学研究表明，斑块破裂是颈动脉相关缺血事件病因学中的关键因素。与斑块破裂相关的特征包括斑块内出血、具有薄覆盖纤维帽的大坏死核心、斑块新生血管和炎性细胞浸润。体内高空间分辨率、多对比度加权磁共振成像（MRI）已被广泛评价，使用组织学作为金标准，并记录了识别这些关键颈动脉斑块特征的可靠性。在这篇图文并茂的文章中，我们说明了MRI识别易破裂和破裂的颈动脉粥样硬化斑块特征的能力。
Stroke is a leading cause of long-term disability and is the third most common cause of death in the United States and western countries. Twenty percent of strokes are thought to arise from the carotid artery. Histopathological studies have suggested that plaque disruption is a key factor in the etiology of carotid-related ischemic events. Features associated with plaque disruption include intraplaque hemorrhage, large necrotic cores with thin overlying fibrous caps, plaque neovasculature and inflammatory cell infiltrate. In vivo high-spatial resolution, multi-contrast weighted magnetic resonance imaging (MRI) has been extensively evaluated using histology as the gold standard, and has documented reliability in the identification of these key carotid plaque features. In this pictorial essay, we illustrate the capability of MRI for identifying features of disruption-prone and disrupted atherosclerotic carotid plaques.
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影响因子：
8.3
作者：
Fisher, M;Paganini-Hill, A;Norris, J
通讯作者：
Norris, J
影响因子：
37.8
作者：
Kampschulte, A;Ferguson, MS;Yuan, C
通讯作者：
Yuan, C
影响因子：
19.7
作者：
Kerwin, William S.;O'Brien, Kevin D.;Yuan, Chun
通讯作者：
Yuan, Chun
动脉粥样硬化的炎症。
DOI：
10.1161/atvbaha.108.179705
发表时间：
2012-09
期刊：
Arteriosclerosis, thrombosis, and vascular biology
影响因子：
--
作者：
Libby P
通讯作者：
Libby P
影响因子：
4.3
作者：
Carr, S;Farb, A;Yao, JST
通讯作者：
Yao, JST