The refractory headache patient--II. High medication consumption (analgesic rebound) headache.
The refractory headache patient--II. High medication consumption (analgesic rebound) headache.
复制标题
顽固性头痛患者--II．
DOI：
10.1016/0005-7967(89)90012-0
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发表时间：
1989
影响因子：
4.1
通讯作者：
Dentinger,MP
中科院分区：
文献类型：
--
作者：
Michultka,DM;Blanchard,EB;Appelbaum,KA;Jaccard,J;Dentinger,MP
“镇痛反跳性头痛”是通过个体对减轻疼痛的药物的习惯、药物消耗后几小时头痛的加重以及药物停止后几周头痛频率和强度的显著增加来确定的。我们描述了三项研究，以澄清这种拟议的头痛综合征的存在和特点。在研究1中，我们比较了一组服用大量止痛药的头痛患者和一组没有服用过量止痛药的头痛患者。结果发现，两组在年龄、头痛问题持续时间或性别上没有差异。然而，两组在主观头痛（高剂量用药者比低剂量用药者经历更多的头痛）和诊断（高剂量用药者更有可能对他们的头痛有肌肉收缩成分）方面确实存在差异。在对高药物组的药物使用进行分析时，发现91%的人服用某种止痛药，大多数人（84%）服用一种以上的药物。在研究2中，我们发现，高药物组在减少头痛活动方面不如匹配对照组成功，这是自我调节行为治疗的结果。此外，在高药物消费人群中，减少和治疗成功之间存在直接关系。最后，在研究3中，我们检查了两组的当前心理功能;两组之间没有发现差异，表明缺乏“成瘾”的人格特征作为高用药人群的解释。这些研究结果都支持存在一个亚群的头痛患者谁消耗过量的止痛药，谁是相对难治的行为治疗。
‘Analgesic rebound headache’ is identified by habituation of an individual to pain reducing medication, the exacerbation of headache pain a few hours after medication consumption and a marked increase in headache frequency and intensity for several weeks after medication is discontinued. We describe three studies undertaken to clarify the existence and characteristics of this proposed headache syndrome. In Study 1 we compared a group of headache sufferers who consume large amounts of analgesic medications to headache sufferers who did not consume excessive analgesics. It was found that the two groups did not differ on age, duration of headache problem or gender. However, the groups did differ on subjective headache pain (with the high medicators experiencing more headache pain than low medicators) and diagnosis (with high medicators being more likely to have a muscle contraction component to their headaches). In an analysis of drug use within the high medication group, it was found that 91% were taking some kind of analgesic and that a majority (84%) were taking more than one type of medication. In Study 2 we found that the group of high medicators were not as successful in reducing headache activity as a result of a self-regulatory behavioral treatment as the matched controls. Furthermore, there was a direct relationship between reduction and treatment success in the high medication consuming population. Lastly, in Study 3 we examined the current psychological functioning of the two groups; no differences were found between the two groups indicating the lack of ‘addictive’ personality characteristics as an explanation for the high medicating population. These findings all support the existence of a sub-population of headache sufferers who consume excessive amounts of analgesic medication and who are relatively refractory to behavioral treatment.
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影响因子：
0.8
作者：
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DOI：
10.1111/j.1526-4610.1987.hed2701030.x
发表时间：
1987
期刊：
Headache: The Journal of Head and Face Pain
影响因子：
--
作者：
T. Sacquegna;P. Cortelli;A. Baldrati;P. Carolis;P. Tinuper
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DOI：
10.1111/j.1526-4610.1976.hed1602070.x
发表时间：
1976
期刊：
Headache: The Journal of Head and Face Pain
影响因子：
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作者：
L. Coyne;J. Sargent;J. Segerson;R. Obourn
通讯作者：
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