Safety of Exercise Testing in the Clinical Chinese Population.
Safety of Exercise Testing in the Clinical Chinese Population.
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DOI：
10.3389/fcvm.2021.638682
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发表时间：
2021
影响因子：
3.6
通讯作者：
Liu S
中科院分区：
文献类型：
--
作者：
Dun Y;Olson TP;Ripley-Gonzalez JW;Xie K;Zhang W;Cai Y;Liu Y;Shen Y;Zhou N;Gong X;Liu S
这项为期18年的横断面研究旨在为中国临床人群中运动试验的安全性提供数据。我们回顾了2002年1月1日至2019年12月31日在中南大学湘雅医院完成的运动试验。从43,130名独立个体(50.9%女性)中，总共检索了50,142项连续测试(标准运动测试29,466项；心肺运动测试20,696项)。描述了人口统计学、患者的病史、运动测试特征和与运动测试相关的不良事件。安全数据以每10,000次测试的不良事件数量表示，可信区间为95%。患者平均年龄(51±13)岁。大多数患者被诊断患有至少一种疾病(N=44,941，89.6%)。测试是最大的或症状受限的。常见临床症状包括头晕(6822例，13.6%)、胸痛或胸闷(2760例，5.5%)、肌肉骨骼受限(2507例，5.0%)。在50,142次试验中，发生了3次不良事件，包括1次持续性室性心动过速，1次窦性心搏骤停，交界性逸搏，频率为28次/分，以及1次晕厥事件，大小便失禁。不良事件发生率男性为每10,000次测试0.8次(95%可信区间，0.2-3.0)，女性为每10,000次测试(0.7-2.2)0.4次，总共为每10,000次测试0.6次(0.21.8)。这项研究是中国临床人群中运动试验最大的数据集分析。我们的结果表明，临床运动试验是安全的，与运动试验相关的不良事件发生率较低可能是由于临床实践随着时间的推移而发生的整体变化。
This 18-year cross-sectional study was conducted to provide data on the safety of exercise testing in the clinical Chinese population. We retrospectively identified exercise tests completed at Xiangya Hospital of Central South University from January 1, 2002 to December 31, 2019. From 43,130 unique individuals (50.9% female), a total of consecutive 50,142 tests (standard exercise testing 29,466; cardiopulmonary exercise testing 20,696) were retrieved. Demographics, patients' medical history, exercise testing characteristics, and exercise testing-related adverse events were described. Safety data is expressed as the number of adverse events per 10,000 tests, with 95% confidence interval. The average patients' age was 51 ± 13 years. The majority of patients were diagnosed with at least one disease (N = 44,941, 89.6%). Tests were maximal or symptom-limited. Common clinical symptoms included dizziness (6,822, 13.6%), chest pain or distress (2,760, 5.5%), and musculoskeletal limitations (2,507, 5.0%). Out of 50,142 tests, three adverse events occurred, including one sustained ventricular tachycardia, one sinus arrest with junctional escape rhythm at a rate of 28 bpm, and one syncopal event with fecal and urinary incontinence. The rate of adverse events was 0.8 events per 10,000 tests (95% confidence interval, 0.2–3.0) in men, 0.4 per 10,000 tests (0.7–2.2) in women, and 0.6 per 10,000 tests (0.21.8) total. This study represents the largest dataset analysis of exercise testing in the clinical Chinese population. Our results demonstrate that clinical exercise testing is safe, and the low rate of adverse events related to exercise testing might be due to the overall changes in clinical practice over time.
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影响因子：
0.6
作者：
WENDT, T;SCHERER, D;KALTENBACH, M
通讯作者：
KALTENBACH, M
DOI：
10.1097/00008483-200007000-00007
发表时间：
2000-07-01
期刊：
Journal of cardiopulmonary rehabilitation
影响因子：
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通讯作者：
Froelicher, V F
影响因子：
9.6
作者：
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通讯作者：
ELLESTAD, MH
DOI：
10.1016/j.jtho.2016.04.021
发表时间：
2016-09
期刊：
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
影响因子：
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作者：
Ha D;Mazzone PJ;Ries AL;Malhotra A;Fuster M
通讯作者：
Fuster M
影响因子：
37.8
作者：
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通讯作者：
Lavie, Carl J.