Leveraging livestock movements to urban slaughterhouses for wide-spread Rift Valley fever virus surveillance in Western Kenya.
Leveraging livestock movements to urban slaughterhouses for wide-spread Rift Valley fever virus surveillance in Western Kenya.
复制标题
利用牲畜运动前往城市屠宰场，以在肯尼亚西部进行广泛的裂谷谷热病毒监测。
DOI：
10.1016/j.onehlt.2022.100457
复制
发表时间：
2022-12
期刊：
影响因子：
5
通讯作者：
LaBeaud, Angelle Desiree
中科院分区：
文献类型：
--
作者：
Gerken, Keli Nicole;Ndenga, Bryson Alberto;Owuor, Kevin Omondi;Winter, Christabel Achieng;Seetah, Krish;LaBeaud, Angelle Desiree
关键词：
Rift Valley fever virus (RVFV) is an economically devastating, zoonotic arbovirus endemic across Africa with potential to cause severe disease in livestock and humans. Viral spread is primarily driven by movement of domestic ruminants and there is a high potential for transboundary spread. Despite influx of livestock to urban areas in response to the high demand for meat and animal products, RVFV has not been detected in any urban center. The objectives of this study were to determine the feasibility of assessing risk of RVFV introduction to urban Kisumu, Kenya, by testing slaughtered livestock for RVFV exposure and mapping livestock origins. Blood was collected from cattle, sheep, and goats directly after slaughter and tested for anti-RVFV IgG antibodies. Slaughterhouse businessmen responded to a questionnaire on their individual animals' origin, marketplace, and transport means. Thereafter, we mapped livestock flow from origin to slaughterhouse using participatory methods in focus group discussions with stakeholders. Qualitative data on route choice and deviations were spatially integrated into the map. A total of 304 blood samples were collected from slaughtered livestock in October and November 2021. Most (99%) of animals were purchased from 28 different markets across eight counties in Western Kenya. The overall RVFV seroprevalence was 9% (19% cattle, 3% in sheep, and 7% in goats). Migori County bordering Tanzania had the highest county-level seroprevalence (34%) and 80% of all seropositive cattle were purchased at the Suba Kuria market in Migori County. Road quality and animal health influenced stakeholders' decisions for choice of transport means. Overall, this proof-of-concept study offers a sampling framework for RVFV that can be locally implemented and rapidly deployed in response to regional risk. This system can be used in conjunction with participatory maps to improve active livestock surveillance and monitoring of RVFV in Western Kenya, and these methods could be extrapolated to other urban centers or livestock diseases. Influx of livestock to urban slaughterhouses increases risk of urban RVFV introduction. Testing urban slaughtered animals for RVFV is feasible and provides animal origin data. A 9% overall RVFV seroprevalence, 18% in cattle, in urban slaughtered ruminants in Kisumu, Kenya Participatory mapping provides critical context to interpret animal origin data and movement. Active surveillance is key to identify RVFV circulation in adult animals that enter urban centers.
登录
查看更多内容
DOI：
10.1093/trstmh/trac076
发表时间：
2022-11-01
影响因子：
2.2
作者：
通讯作者：
--
DOI：
10.1371/journal.pgph.0000505
发表时间：
2022
期刊：
PLOS global public health
影响因子：
--
作者：
通讯作者：
--
影响因子：
16.8
作者：
Hassell, James M.;Begon, Michael;Ward, Melissa J.;Fevre, Eric M.
通讯作者：
Fevre, Eric M.
影响因子：
5
作者：
Floyd, Jessica R.;Ruktanonchai, Nick W.;Fevre, Eric M.
通讯作者：
Fevre, Eric M.
影响因子：
5.2
作者：
Schreur, Paul J. Wichgers;van Keulen, Lucien;Kortekaas, Jeroen
通讯作者：
Kortekaas, Jeroen