Construction of a multisite DataLink using electronic health records for the identification, surveillance, prevention, and management of diabetes mellitus: the SUPREME-DM project.

Construction of a multisite DataLink using electronic health records for the identification, surveillance, prevention, and management of diabetes mellitus: the SUPREME-DM project.
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DOI:
10.5888/pcd9.110311
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发表时间:
2012
影响因子:
5.5
通讯作者:
SUPREME-DM Study Group
SUPREME-DM Study Group
中科院分区:
医学3区
文献类型:
--
作者:
Nichols GA;Desai J;Elston Lafata J;Lawrence JM;O'Connor PJ;Pathak RD;Raebel MA;Reid RJ;Selby JV;Silverman BG;Steiner JF;Stewart WF;Vupputuri S;Waitzfelder B;SUPREME-DM Study Group

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电子健康记录(EHR)数据增加了对糖尿病进行监测的机会。本研究的目的是从糖尿病数据链中确定糖尿病患者的数量,该数据链是SUPREME-DM(糖尿病监测、预防和管理)项目的一部分,该项目是一个由11个综合卫生系统组成的联盟,使用全面的EHR数据进行研究。我们确定了2005年1月至2009年12月期间有任何登记的11个医疗保健系统的所有成员。对于这些成员,我们搜索了2000年1月至2009年12月的住院和门诊诊断代码,实验室检查结果和药物分配,以创建可能识别糖尿病患者的指标变量。使用这些信息,我们估计了糖尿病患者的数量,其中,事件病例的数量,定义为至少2年连续卫生系统登记后的糖尿病指征。11个卫生系统贡献了15,765,529名独立成员,其中1,085,947人(6.9%)符合1项或多项糖尿病研究标准。各研究中心符合糖尿病研究标准的非标准化比例范围为4.2%至12.4%。大多数糖尿病患者(88%)符合多项标准。在糖尿病患者中,428,349人(39.4%)为偶发病例。SUPREME-DM DataLink是一种独特的资源,为进行比较有效性研究、流行病学监测(包括纵向分析)和糖尿病患者基于人群的护理管理研究提供了机会。它还为预防或治疗干预的实用临床试验提供了有用的数据来源。
Electronic health record (EHR) data enhance opportunities for conducting surveillance of diabetes. The objective of this study was to identify the number of people with diabetes from a diabetes DataLink developed as part of the SUPREME-DM (SUrveillance, PREvention, and ManagEment of Diabetes Mellitus) project, a consortium of 11 integrated health systems that use comprehensive EHR data for research. We identified all members of 11 health care systems who had any enrollment from January 2005 through December 2009. For these members, we searched inpatient and outpatient diagnosis codes, laboratory test results, and pharmaceutical dispensings from January 2000 through December 2009 to create indicator variables that could potentially identify a person with diabetes. Using this information, we estimated the number of people with diabetes and among them, the number of incident cases, defined as indication of diabetes after at least 2 years of continuous health system enrollment. The 11 health systems contributed 15,765,529 unique members, of whom 1,085,947 (6.9%) met 1 or more study criteria for diabetes. The nonstandardized proportion meeting study criteria for diabetes ranged from 4.2% to 12.4% across sites. Most members with diabetes (88%) met multiple criteria. Of the members with diabetes, 428,349 (39.4%) were incident cases. The SUPREME-DM DataLink is a unique resource that provides an opportunity to conduct comparative effectiveness research, epidemiologic surveillance including longitudinal analyses, and population-based care management studies of people with diabetes. It also provides a useful data source for pragmatic clinical trials of prevention or treatment interventions.
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